SCHEMBL3404192

SCHEMBL3404192

OC(Cl)[C@H]1O[C@@H](n2cnc3cncnc32)[C@H](O)[C@@H]1O

nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DNMT3B Q9UBC3 1/20 0.53
PRMT5 O14744 6/20 0.45
WDR77 Q9BQA1 6/20 0.45
AHCY P23526 1/20 0.42
ADA P00813 1/20 0.41
KDM4E B2RXH2 1/20 0.40
PKM P14618 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18486632 0.86 DNMT3B (0.47) DNMT3B
SCHEMBL4621109 0.85 DNMT3B (0.52) DNMT3BPRMT5WDR77AHCYADA
SCHEMBL17515059 0.84 DNMT3B (0.47) DNMT3BPRMT5WDR77AHCYADA
SCHEMBL11568109 0.84 DNMT3B (0.47) DNMT3B
SCHEMBL18486651 0.83 DNMT3B (0.44) DNMT3B
SCHEMBL7170446 0.82 ADORA3 (0.56) DNMT3B
SCHEMBL18486626 0.82 DNMT3B (0.44) DNMT3B
Nebularine SCHEMBL10666450 0.80 ADA (0.65) DNMT3BADAKDM4EPKM
Nebularine SCHEMBL9644429 0.80 ADA (0.65) DNMT3BADAKDM4EPKM
Nebularine SCHEMBL742475 0.80 ADA (0.65) DNMT3BADAKDM4EPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2204154-B1 Association of monosaccharides and adenosine and its cosmetic use ORÉAL L (FR) 2016-10-12 EP claimed
EP-2204154-A1 Association of monosaccharides and adenosine and its cosmetic use L'OREAL (FR) 2010-07-07 EP claimed
US-20100168049-A1 COMBINATION OF MONOSACCHARIDES AND ADENOSINE AND USE THEREOF L'OREAL (FR) 2010-07-01 US claimed
US-20260103480-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME SANOFI SA (FR) 2026-04-16 US disclosed
US-20240376137-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME SANOFI SA (FR) 2024-11-14 US disclosed
US-11897911-B2 Nucleotide precursors, nucleotide analogs and oligomeric compounds containing the same SANOFI (FR) 2024-02-13 US disclosed
US-20220372063-A1 OLIGONUCLEOTIDES CONTAINING NUCLEOTIDE ANALOGS SANOFI (FR) 2022-11-24 US disclosed
EP-4025582-A1 OLIGONUCLEOTIDES CONTAINING NUCLEOTIDE ANALOGS SANOFI (FR) 2022-07-13 EP disclosed
CN-114728999-A Oligonucleotides containing nucleotide analogs 赛诺菲 2022-07-08 CN disclosed
EP-3762395-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME Sanofi (FR) 2021-01-13 EP disclosed
WO-2019170731-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME SANOFI (FR) 2019-09-12 WO disclosed
EP-1019426-A1 NOVEL A 1? ADENOSINE RECEPTOR AGONISTS AND ANTAGONISTS THE UNIVERSITY OF FLORIDA (US) 2000-07-19 EP disclosed
WO-1997024363-A1 NOVEL A1 ADENOSINE RECEPTOR AGONISTS AND ANTAGONISTS UNIVERSITY OF FLORIDA (US) 1997-07-10 WO disclosed
US-5055569-A Gastrointestinal disorders G. D. SEARLE & CO. (US) 1991-10-08 US disclosed
EP-0423777-A2 Method of treating gastrointestinal motility disorders G.D. Searle & Co. (US) 1991-04-24 EP disclosed
EP-0423776-A2 N-(6)-substituted adenosine compounds G.D. Searle & Co. (US) 1991-04-24 EP disclosed
EP-0179631-B1 N6-ACENAPHTHYL ADENOSINES AND ANALOGS THEREOF WARNER-LAMBERT COMPANY (US) 1989-04-26 EP disclosed
US-4673670-A TREATING ANGINA WARNER-LAMBERT COMPANY (US) 1987-06-16 US disclosed
US-4614732-A HYPOTENSIVE AGENTS WARNER-LAMBERT COMPANY (US) 1986-09-30 US disclosed
EP-0179631-A2 N6-acenaphthyl adenosines and analogs thereof WARNER-LAMBERT COMPANY (US) 1986-04-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11897911-B2 Nucleotide precursors, nucleotide analogs and oligomeric compounds containing the same RNMT, RRM2B, RRM2 DNMT3B 493/4885PRMT5 2920/4885WDR77 368/4885
US-20260103480-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME NSUN2, NSUN3, SNRPA DNMT3B 206/4885PRMT5 3623/4885WDR77 663/4885
US-20100168049-A1 COMBINATION OF MONOSACCHARIDES AND ADENOSINE AND USE THEREOF ADORA2A, ADORA1, ADORA3 DNMT3B 1675/4885PRMT5 715/4885WDR77 910/4885
US-20240376137-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME RNMT, NSUN2, ADAR DNMT3B 406/4885PRMT5 3537/4885WDR77 572/4885
US-20220372063-A1 OLIGONUCLEOTIDES CONTAINING NUCLEOTIDE ANALOGS DCLRE1B, UPF1, IGF2BP1 DNMT3B 861/4885PRMT5 3223/4885WDR77 607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.