Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL338472 | 0.98 | GPR84 (0.42) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL339821 | 0.95 | ALOX15 (0.43) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL23920298 | 0.89 | HSD17B10 (0.46) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL11511199 | 0.85 | USP2 (0.39) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL11509033 | 0.85 | ADRB1 (0.46) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL11511249 | 0.85 | USP2 (0.39) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL1839374 | 0.83 | USP2 (0.44) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL3657095 | 0.82 | CYP3A4 (0.49) | ALOX15 | |
| SCHEMBL11781156 | 0.81 | USP2 (0.42) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL1836601 | 0.81 | USP2 (0.42) | USP2ALDH1A1GAAPKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2271651-B1 | ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-01-01 | — | — | EP | disclosed |
| EP-2346887-B1 | SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES | DOW TECHNOLOGY INVESTMENTS LLC (US) | 2013-12-25 | — | — | EP | disclosed |
| US-8546600-B2 | Slurry process for synthesis of bisphosphites and situ use thereof for producing bisphosphite | DOW TECHNOLOGY INVESTMENTS LLC | 2013-10-01 | — | — | US | disclosed |
| EP-2257560-B1 | SLURRY PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS | UNION CARBIDE CHEM PLASTIC (US) | 2013-07-17 | — | — | EP | disclosed |
| US-8471066-B2 | Slurry process for phosphoromonochloridite synthesis | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC | 2013-06-25 | — | — | US | disclosed |
| US-8097749-B2 | Isothermal process for phosphoromonochloridite synthesis | Union Carbide Chemical and Plastics Technology Technology | 2012-01-17 | — | — | US | disclosed |
| US-20110196166-A1 | SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES AND SITU USE THEREOF FOR PRODUCING BISPHOSPHITE | DOW TECHNOLOGY INVESTMENTS LLC | 2011-08-11 | — | — | US | disclosed |
| EP-2346887-A1 | SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES | Dow Technology Investments LLC (US) | 2011-07-27 | — | — | EP | disclosed |
| US-20110021840-A1 | SLURRY PROCESS FOR PHOSPHOROMONOCHLORIDITE SYTHESIS | UNION CARBIDE CORPORATION | 2011-01-27 | — | — | US | disclosed |
| EP-2271651-A1 | ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS | Dow Global Technologies Inc. (US) | 2011-01-12 | — | — | EP | disclosed |
| WO-2010042313-A1 | SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES | DOW TECHNOLOGY INVESTMENTS LLC (US) | 2010-04-15 | — | — | WO | disclosed |
| WO-2009120210-A1 | ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2009-10-01 | — | — | WO | disclosed |
| US-20090247790-A1 | ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS | UNION CARBIDE CORPORATION | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247790-A1 | ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS | PIM3, PLCB3, PLCD1 | USP2 3345/4885ALDH1A1 4149/4885GAA 3173/4885 |
| US-20110196166-A1 | SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES AND SITU USE THEREOF FOR PRODUCING BISPHOSPHITE | SOST, PLCB3, PPIP5K2 | USP2 3836/4885ALDH1A1 4653/4885GAA 4660/4885 |
| US-20110021840-A1 | SLURRY PROCESS FOR PHOSPHOROMONOCHLORIDITE SYTHESIS | PSPH, SPIN3, SYNGR2 | USP2 1842/4885ALDH1A1 4865/4885GAA 4310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.