Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CCR6 | P51684 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 3/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | HTR5A | P47898 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5707829 | 0.90 | ADRB1 (0.56) | HTR6ALDH1A1USP2TSHRHSD17B10 | |
| SCHEMBL5707831 | 0.88 | HTR6 (0.60) | HTR6ALDH1A1USP2TSHRHSD17B10 | |
| SCHEMBL109882 | 0.85 | ADRB1 (0.55) | HTR6ALDH1A1USP2TSHRHSD17B10 | |
| SCHEMBL28529587 | 0.85 | LMNA (0.57) | HTR6ALDH1A1TSHRHSD17B10HSP90AA1 | |
| SCHEMBL28325052 | 0.85 | NPC1 (0.62) | HTR6ALDH1A1TSHRHSD17B10HSP90AA1 | |
| SCHEMBL28283430 | 0.83 | ADRB1 (0.53) | HTR6ALDH1A1USP2TSHRHSD17B10 | |
| SCHEMBL29761689 | 0.83 | ADRB1 (0.53) | HTR6ALDH1A1USP2TSHRHSD17B10 | |
| SCHEMBL10684744 | 0.83 | NPC1 (0.65) | HTR6ALDH1A1USP2TSHRHSD17B10 | |
| SCHEMBL2869405 | 0.83 | HTR6 (0.61) | HTR6ALDH1A1USP2TSHRHSD17B10 | |
| SCHEMBL2323487 | 0.81 | ALDH1A1 (0.64) | ALDH1A1TSHRHSP90AA1PKMCCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262809-A1 | BENZOPHENONE-PIPERAZINE LINKED PYRROLO[2,1-C][1,4]BENZODIAZEPINE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF | Council Of Scientific & Industrial Research (IN) | 2010-12-22 | — | — | EP | claimed |
| WO-2009118749-A1 | BENZOPHENONE-PIPERAZINE LINKED PYRROLO[2,1-C][1,4]BENZODIAZEPINE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-10-01 | — | — | WO | claimed |
| EP-2459519-B1 | MACROPHOTOINITIATORS | BASF SE (DE) | 2017-11-29 | — | — | EP | disclosed |
| CN-101851497-B | Photochromic materials with reactive substituents | TRANSITIONS OPTICAL INC | 2015-06-10 | — | — | CN | disclosed |
| US-8906979-B2 | Macrophotoinitiators | BASF SE (DE) | 2014-12-09 | — | — | US | disclosed |
| CN-102977080-A | Photochromic materials with reactive substituents | TRANSITIONS OPTICAL INC | 2013-03-20 | — | — | CN | disclosed |
| CN-101180575-B | Photochromic materials with reactive substituents | TRANSITIONS OPTICAL INC | 2013-01-02 | — | — | CN | disclosed |
| US-20120178844-A1 | MACROPHOTOINITIATORS | BASF SE (DE) | 2012-07-12 | — | — | US | disclosed |
| CN-102250044-A | Piperazino photoinitiation sensitiser | SUN CHEMICAL CORP | 2011-11-23 | — | — | CN | disclosed |
| CN-1914185-B | Piperazine-based sensitizer | SUN CHEMICAL CORP | 2011-06-29 | — | — | CN | disclosed |
| CN-101921184-A | Multi-functional group type aromatic ketone compound and photoinitiator containing same | SHENZHEN YOUWEI CHEMICAL TECHNOLOGY CO LTD | 2010-12-22 | — | — | CN | disclosed |
| CN-101851497-A | Photochromic material with reactive substituents | TRANSITIONS OPTICAL INC | 2010-10-06 | — | — | CN | disclosed |
| CN-101180575-A | Photochromic materials with reactive substituents | TRANSITIONS OPTICAL INC (US) | 2008-05-14 | — | — | CN | disclosed |
| CN-1914185-A | Piperazine-based sensitizer | SUN CHEMICAL CORP (US) | 2007-02-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178844-A1 | MACROPHOTOINITIATORS | CD68, CD209, MSR1 | HTR6 1281/4885ALDH1A1 1147/4885USP2 3078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.