Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29381329 | 1.00 | GABRA1 (0.33) | GABRA1GABRB2BCHEACHERIPK1 | |
| SCHEMBL4444608 | 0.97 | BCHE (0.32) | GABRA1GABRB2BCHEACHERIPK1 | |
| SCHEMBL4449614 | 0.95 | RIPK1 (0.34) | GABRA1GABRB2BCHEACHERIPK1 | |
| SCHEMBL30872867 | 0.91 | PNMT (0.32) | PNMTIDO1ALDH1A1MEN1KMT2A | |
| SCHEMBL17750351 | 0.91 | GABRA1 (0.43) | GABRA1GABRB2ALDH1A1MEN1KMT2A | |
| SCHEMBL20732795 | 0.87 | RIPK1 (0.33) | RIPK1 | |
| SCHEMBL3680536 | 0.86 | TAAR1 (0.43) | ACHEALDH1A1MEN1KMT2ATAAR1 | |
| SCHEMBL1948544 | 0.85 | RIPK1 (0.32) | RIPK1SLC6A2 | |
| SCHEMBL1423269 | 0.85 | CYP3A4 (0.31) | RIPK1 | |
| SCHEMBL5598297 | 0.84 | TAAR1 (0.42) | RIPK1IDO1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 488 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12637412-B2 | Preparation of aromatic carboxyamides by a palladium-catalyzed carbonylation reaction | BASF SE (DE) | 2026-05-26 | — | — | US | claimed |
| US-12595223-B2 | Propionic acid process | EASTMAN CHEMICAL COMPANY (US) | 2026-04-07 | — | — | US | claimed |
| EP-4143158-B1 | PREPARATION OF AROMATIC CARBOXYAMIDES BY PALLADIUM-CATALYZED CARBONYLATION REACTION | BASF SE (DE) | 2025-10-01 | — | — | EP | claimed |
| EP-2427468-B2 | PREPARATION OF A METAL COMPLEX | JOHNSON MATTHEY PLC (GB) | 2025-06-04 | — | — | EP | claimed |
| EP-3694864-B1 | BORONIC ACID DERIVATIVES AND SYNTHESIS THEREOF | QPEX BIOPHARMA INC (US) | 2025-03-05 | — | — | EP | claimed |
| CN-117986119-A | Method for preparing carboxylic ester by using sulfonic acid resin in olefin hydroesterification reaction | 中国石油化工股份有限公司 | 2024-05-07 | — | — | CN | claimed |
| EP-4143159-B1 | PREPARATION OF AROMATIC CARBOXYAMIDES BY A PALLADIUM-CATALYZED CARBONYLATION REACTION | BASF SE (DE) | 2024-04-10 | — | — | EP | claimed |
| US-20240002324-A1 | PROPIONIC ACID PROCESS | EASTMAN CHEMICAL COMPANY (US) | 2024-01-04 | — | — | US | claimed |
| EP-4267591-A2 | ORGANOMETALLIC COMPOUNDS | Umicore AG & Co. KG (DE) | 2023-11-01 | — | — | EP | claimed |
| US-20230339847-A1 | PREPARATION OF AROMATIC CARBOXYAMIDES BY A PALLADIUM-CATALYZED CARBONYLATION REACTION | BASF SE (DE) | 2023-10-26 | — | — | US | claimed |
| US-6743911-B2 | PENTENENITRILE REACTED WITH CARBON MONOXIDE AND WATER OR ALCOHOL IN THE PRESENCE OF A SOURCE OF GROUP VIII METAL AND A BIDENTATE PHOSPHINE, ARSINE AND/OR STIBINE LIGAND TO FORM CYANOVALERIC ACID OR ESTER | SHELL OIL COMPANY | 2004-06-01 | — | — | US | claimed |
| EP-1263713-B1 | PROCESS FOR THE CARBONYLATION OF PENTENENITRILE | SHELL INT RESEARCH (NL) | 2004-05-12 | — | — | EP | claimed |
| EP-1064288-B1 | PROCESS FOR THE PREPARATION OF BISPHOSPHINES | LUCITE INT UK LTD (GB) | 2003-05-02 | — | — | EP | claimed |
| US-6489506-B2 | USING A HIGH MOLAR RATIO OF ETHYLENE TO CARBON MONOXIDE IN THE GAS IN CONTACT WITH THE LIQUID PHASE TO IMPROVE ACTIVITY AND LIFE OF THE CATALYST | LUCITE INTERNATIONAL UK LIMITED (GB) | 2002-12-03 | — | — | US | claimed |
| US-6376715-B1 | FROM AN ORGANOMETALLIC COMPOUND | INEOS ACRYLICS U.K. LIMITED (GB) | 2002-04-23 | — | — | US | claimed |
| US-20020045748-A1 | Process for the carbonylation of pentenenitrile | SHELL OIL COMPANY | 2002-04-18 | — | — | US | claimed |
| EP-0970038-B1 | PROCESS FOR THE CARBONYLATION OF ETHYLENE | INEOS ACRYLICS UK LTD (GB) | 2002-04-10 | — | — | EP | claimed |
| US-6284919-B1 | LIQUID PHASE CARBONYLATION OF ETHYLENE USING CARBON MONOXIDE IN THE PRESENCE OF PALLADIUM WITH PHOSPHINE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 2001-09-04 | — | — | US | claimed |
| EP-1064288-A1 | PROCESS FOR THE PREPARATION OF BISPHOSPHINES | Ineos Acrylics UK Limited (GB) | 2001-01-03 | — | — | EP | claimed |
| WO-1999047528-A1 | PROCESS FOR THE PREPARATION OF BISPHOSPHINES | INEOS ACRYLICS UK LIMITED (GB) | 1999-09-23 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12637412-B2 | Preparation of aromatic carboxyamides by a palladium-catalyzed carbonylation reaction | CBR3, CBR1, AOC1 | GABRA1 2727/4885GABRB2 2779/4885BCHE 1158/4885 |
| US-12595223-B2 | Propionic acid process | HAO2, MVD, TMCO1 | GABRA1 3293/4885GABRB2 3286/4885BCHE 4827/4885 |
| US-20020045748-A1 | Process for the carbonylation of pentenenitrile | PRKCE, PRKCB, PRKCH | GABRA1 1182/4885GABRB2 1415/4885BCHE 552/4885 |
| US-20230339847-A1 | PREPARATION OF AROMATIC CARBOXYAMIDES BY A PALLADIUM-CATALYZED CARBONYLATION REACTION | CBR3, CBR1, DDT | GABRA1 3461/4885GABRB2 3068/4885BCHE 670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.