Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.69 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.69 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.69 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.69 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.69 |
| ▸ | DRD1 | P21728 | 1/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.69 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.69 |
| ▸ | HRH1 | P35367 | 1/20 | 0.69 |
| ▸ | DRD3 | P35462 | 1/20 | 0.69 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.69 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.69 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.69 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18546398 | 0.98 | ADRB2 (0.72) | ADRB2ADORA3CHRM1ADRA2BADRA2C | |
| SCHEMBL29245172 | 0.98 | ADRB2 (0.72) | ADRB2ADORA3CHRM1ADRA2BADRA2C | |
| SCHEMBL28565282 | 0.95 | DRD1 (0.67) | ADRB2ADORA3CHRM1ADRA2BADRA2C | |
| SCHEMBL19358636 | 0.90 | MAPT (0.68) | ADRB2ADORA3CHRM1ADRA2BADRA2C | |
| SCHEMBL29936449 | 0.90 | MAPT (0.68) | ADRB2ADORA3CHRM1ADRA2BADRA2C | |
| SCHEMBL29517055 | 0.89 | MAPT (0.69) | ADRB2ADORA3CHRM1ADRA2BADRA2C | |
| SCHEMBL94205 | 0.89 | MAPT (0.69) | ADRB2ADORA3CHRM1ADRA2BADRA2C | |
| SCHEMBL94204 | 0.89 | MAPT (0.69) | ADRB2ADORA3CHRM1ADRA2BADRA2C | |
| SCHEMBL9503350 | 0.88 | MAPT (0.65) | ADRB2ADORA3CHRM1ADRA2BADRA2C | |
| SCHEMBL11811440 | 0.86 | ADRB2 (0.73) | ADRB2ADORA3CHRM1ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103547566-B | Aminoindane compounds and their use to treat pain | 阿萨纳生物科技有限责任公司 | 2017-05-31 | — | — | CN | claimed |
| CN-106232110-A | Ion channel activation agent and using method | 弗莱克斯制药股份有限公司 | 2016-12-14 | — | — | CN | claimed |
| CN-105777573-A | Preparation method of N-coumaroyldopamine | 海门德思行药业科技有限公司 | 2016-07-20 | — | — | CN | claimed |
| CN-102112121-A | Methods, compositions, and kits for treating pain and pruritis | HARVARD COLLEGE | 2011-06-29 | — | — | CN | claimed |
| CN-113710235-B | Oral cannabinoid tablet | 诺狄更斯公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-113329743-B | Tableted cannabinoid chewing gum with polyvinyl acetate elastomer plasticizer | 诺狄更斯公司 | 2023-09-05 | — | — | CN | disclosed |
| WO-2023139581-A1 | MODULATORS OF A POTASSIUM CHANNEL AND OF TRPV1 CHANNEL AND USES THEREOF | BSENSE BIO THERAPEUTICS LTD. (IL) | 2023-07-27 | — | — | WO | disclosed |
| CN-113784704-A | Rapidly disintegrating cannabinoid tablets | 诺狄更斯公司 | 2021-12-10 | — | — | CN | disclosed |
| CN-113727704-A | Cannabinoid lozenge formulations | 诺狄更斯公司 | 2021-11-30 | — | — | CN | disclosed |
| CN-113710235-A | Oral cannabinoid tablets | 诺狄更斯公司 | 2021-11-26 | — | — | CN | disclosed |
| CN-108601826-B | Immunostimulatory compositions | 法国公立援助医院 | 2021-10-26 | — | — | CN | disclosed |
| WO-2021188084-A2 | A MEASUREMENT SYSTEM FOR TEAR CHEMICALS IN THE TEAR FOR DIAGNOSING DISEASES | VSY BIYOTEKNOLOJI VE ILAC SANAYI ANONIM SIRKETI (TR) | 2021-09-23 | — | — | WO | disclosed |
| US-20100137296-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2010-06-03 | — | — | US | disclosed |
| CN-101522181-A | Use of hypothermia inducing drugs to treat ischemia | NEUROKEY AS (DK) | 2009-09-02 | — | — | CN | disclosed |
| US-20090197823-A1 | ALISKIREN MODULATION OF NEUROGENESIS | BRAINCELLS, INC. (US) | 2009-08-06 | — | — | US | disclosed |
| WO-2009037707-A2 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2009-03-26 | — | — | WO | disclosed |
| WO-2003007875-A9 | COMPOUNDS WITH ANALGESIC, ANTIPYRETIC AND/OR ANTI-INFLAMMATORY ACTIVITY | HOEGESTAETT EDWARD (SE) | 2005-03-10 | — | — | WO | disclosed |
| US-20040209959-A1 | Congeners of acetaminophen and related compounds as substrates for fatty acid conjugation and their use in treatment of pain, fever and inflammation | HOGESTATT EDWARD (SE) | 2004-10-21 | — | — | US | disclosed |
| WO-2003008632-A1 | FATTY ACID CONJUGATION AS A METHOD FOR SCREENING OF POTENTIALLY BIOACTIVE SUBSTANCES | HOEGESTAETT EDWARD (SE) | 2003-01-30 | — | — | WO | disclosed |
| WO-2003007875-A2 | COMPOUNDS WITH ANALGESIC, ANTIPYRETIC AND/OR ANTI-INFLAMMATORY ACTIVITY | HOEGESTAETT EDWARD (SE) | 2003-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090197823-A1 | ALISKIREN MODULATION OF NEUROGENESIS | DCX, NGF, BDNF | ADRB2 513/4885ADORA3 1906/4885CHRM1 1549/4885 |
| US-20040209959-A1 | Congeners of acetaminophen and related compounds as substrates for fatty acid conjugation and their use in treatment of pain, fever and inflammation | ACOX3, CYP2E1, CYP3A43 | ADRB2 1428/4885ADORA3 604/4885CHRM1 3122/4885 |
| US-20100137296-A1 | N-PHENYL ANTHRANILIC ACID DERIVATIVES AND USES THEREOF | TRPV1, TRPA1, TRPV4 | ADRB2 965/4885ADORA3 490/4885CHRM1 1100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.