Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 10/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | DDO | Q99489 | 5/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | COMT | P21964 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3360150 | 0.81 | DAO (0.59) | DAOKMT2ADDOMEN1HTT | |
| SCHEMBL3419432 | 0.78 | DAO (0.51) | DAOKMT2ADDOMEN1LMNA | |
| SCHEMBL29951361 | 0.74 | PIM1 (0.36) | KMT2AMAPTMEN1LMNAKDR | |
| SCHEMBL3360159 | 0.73 | DAO (0.58) | DAODDO | |
| SCHEMBL3359175 | 0.72 | DAO (0.64) | DAOKMT2ADDOMAPTMEN1 | |
| SCHEMBL3434396 | 0.71 | DAO (0.47) | DAOKMT2ADDO | |
| SCHEMBL3361211 | 0.70 | DAO (0.53) | DAODDOMAPT | |
| SCHEMBL9389416 | 0.70 | DAO (0.66) | DAODDO | |
| SCHEMBL29985445 | 0.69 | CDK1 (0.55) | KMT2AMAPTMEN1LMNAHTT | |
| SCHEMBL3418623 | 0.69 | DAO (0.64) | DAOKMT2ADDOMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |