Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.36 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.30 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.30 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28394791 | 1.00 | KDM4E (0.50) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| SCHEMBL125497 | 1.00 | — | — | |
| Ammonia Solution, Strong SCHEMBL27752877 | 0.97 | — | — | |
| SCHEMBL7750776 | 0.97 | — | — | |
| SCHEMBL25252386 | 0.93 | — | — | |
| SCHEMBL587040 | 0.93 | KDM4E (0.43) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| SCHEMBL1404436 | 0.93 | KDM4E (0.43) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| SCHEMBL1138504 | 0.93 | KDM4E (0.43) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| SCHEMBL2293214 | 0.93 | KDM4E (0.43) | KDM4EMAPTALOX15ALDH1A1TSHR | |
| Zinc Ion SCHEMBL491189 | 0.93 | KDM4E (0.43) | KDM4EMAPTALOX15ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6283336-B1 | Article for the delivery of foam products | THE PROCTER & GAMBLE COMPANY | 2001-09-04 | — | — | US | claimed |
| CN-111116430-B | Preparation method of sodium taurate | 万华化学集团股份有限公司 | 2022-04-22 | — | — | CN | disclosed |
| CN-111116430-A | Preparation method of sodium taurate | 万华化学集团股份有限公司 | 2020-05-08 | — | — | CN | disclosed |
| EP-1889322-B1 | BLEND OF IONIC (CO) POLYMER RESINS AND MATRIX (CO) POLYMERS | ARKEMA INC (US) | 2013-02-20 | — | — | EP | disclosed |
| US-7815986-B2 | membrane-electrode assemblies for use in fuel cells; polyelectrolyte copolymer containing units from a sulfonate-, phosphonate- or carboxylate-functionalized styrene and crosslinkable units, e.g., tetraalkylammonium salt of a vinylbenzylsulfonic acid-vinylbenzyl alcohol copolymer | ARKEMA INC. (US) | 2010-10-19 | — | — | US | disclosed |
| US-7803891-B2 | Polyelectrolyte styrenic polymers having sulfonate, carboxylate or phosphonate groups as well as crosslinking groups; blend with a tough, and highly chemical-resistant polymer, preferably a fluoropolymer; Membrane-Electrode Assemblies for use in fuel cells | ARKEMA INC. (US) | 2010-09-28 | — | — | US | disclosed |
| US-7781529-B2 | Polyelectrolyte vinyl alcohol polymers having sulfonate, carboxylate or phosphonate groups as well as crosslinking groups; blend with a tough, and highly chemical-resistant polymer, preferably a fluoropolymer; Membrane-Electrode Assemblies for use in fuel cells | ARKEMA INC. (US) | 2010-08-24 | — | — | US | disclosed |
| US-7629426-B2 | Polyelectrolyte vinyl alcohol polymers having sulfonate, carboxylate or phosphonate groups as well as crosslinking groups; blend with a tough, and highly chemical-resistant polymer, preferably a fluoropolymer; Membrane-Electrode Assemblies for use in fuel cells | ARKEMA INC. (US) | 2009-12-08 | — | — | US | disclosed |
| US-20080242819-A1 | Polyelectrolyte vinyl alcohol polymers having sulfonate, carboxylate or phosphonate groups as well as crosslinking groups; blend with a tough, and highly chemical-resistant polymer, preferably a fluoropolymer; Membrane-Electrode Assemblies for use in fuel cells | ARKEMA INC. (US) | 2008-10-02 | — | — | US | disclosed |
| US-20080242805-A1 | Polyelectrolyte vinyl alcohol polymers having sulfonate, carboxylate or phosphonate groups as well as crosslinking groups; blend with a tough, and highly chemical-resistant polymer, preferably a fluoropolymer; Membrane-Electrode Assemblies for use in fuel cells | ARKEMA INC. (US) | 2008-10-02 | — | — | US | disclosed |
| US-20080241630-A1 | membrane-electrode assemblies for use in fuel cells; polyelectrolyte copolymer containing units from a sulfonate-, phosphonate- or carboxylate-functionalized styrene and crosslinkable units, e.g., tetraalkylammonium salt of a vinylbenzylsulfonic acid-vinylbenzyl alcohol copolymer | ARKEMA INC. (US) | 2008-10-02 | — | — | US | disclosed |
| US-20080242833-A1 | BLEND OF IONIC (CO)POLYMER RESINS AND MATRIX (CO)POLYMERS | ARKEMA INC. (US) | 2008-10-02 | — | — | US | disclosed |
| US-7396880-B2 | Polyelectrolyte copolymer containing units from a sulfonate-, phosphonate- or carboxylate-functionalized styrene and crosslinkable units, e.g., tetraalkylammonium salt of a vinylbenzylsulfonic acid-vinylbenzyl alcohol copolymer; useful for membrane-electrode assemblies for use in fuel cells | ARKEMA INC. (US) | 2008-07-08 | — | — | US | disclosed |
| EP-1889322-A2 | BLEND OF IONIC (CO) POLYMER RESINS AND MATRIX (CO) POLYMERS | Arkema Inc. (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006127309-A2 | BLEND OF IONIC (CO) POLYMER RESINS AND MATRIX (CO) POLYMERS | ARKEMA INC. (US) | 2006-11-30 | — | — | WO | disclosed |
| US-20060269815-A1 | Polyelectrolyte copolymer containing units from a sulfonate-, phosphonate- or carboxylate-functionalized styrene and crosslinkable units, e.g., tetraalkylammonium salt of a vinylbenzylsulfonic acid-vinylbenzyl alcohol copolymer; useful for membrane-electrode assemblies for use in fuel cells | ARKEMA INC. | 2006-11-30 | — | — | US | disclosed |