Sugi Predict

Sugi Predict / Compounds / SCHEMBL34330

SCHEMBL34330

SCHEMBL34330

CC(C)CC=C1C(=O)CC(C)(C)CC1=O

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 10/20 0.40
▸ MAPT P10636 7/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.40
▸ POLB P06746 1/20 0.37
▸ TSHR P16473 1/20 0.36
▸ MAOA P21397 1/20 0.35
▸ GAA P10253 2/20 0.35
▸ KDM4E B2RXH2 3/20 0.34
▸ PTGES O14684 1/20 0.34
▸ ALOX5 P09917 1/20 0.34
▸ HTT P42858 3/20 0.33
▸ TP53 P04637 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ APP P05067 1/20 0.33
▸ GLA P06280 1/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29238572 0.85 ALDH1A1 (0.38) ALDH1A1MAPTL3MBTL1POLBTSHR
SCHEMBL22361676 0.73 MAPT (0.35) ALDH1A1MAPTL3MBTL1POLBTSHR
SCHEMBL26502837 0.69 PTGES (0.34) PTGESALOX5
SCHEMBL20572461 0.69 ALDH1A1 (0.38) ALDH1A1MAPTL3MBTL1POLBTSHR
SCHEMBL60469 0.69 ALDH1A1 (0.47) ALDH1A1MAPTL3MBTL1POLBMAOA
SCHEMBL18871416 0.67 ALDH1A1 (0.46) ALDH1A1MAPTL3MBTL1POLBMAOA
SCHEMBL581954 0.67 ALDH1A1 (0.46) ALDH1A1MAPTL3MBTL1POLBMAOA
SCHEMBL27195624 0.67 MAPT (0.50) ALDH1A1MAPTPOLBTSHRGAA
SCHEMBL2324941 0.67 — —
SCHEMBL4928133 0.64 ALDH1A1 (0.40) ALDH1A1MAPTL3MBTL1POLBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1296 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240116981-A1 TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES FOR PEPTIDE PURIFICATION Belyntic GmbH (DE) 2024-04-11 — — US claimed
US-11884612-B2 Covalent peptide binders THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-01-30 — — US claimed
US-20230303502-A1 HETEROARYL AND HETEROCYCLYL COMPOUNDS SIGILON THERAPEUTICS, INC. 2023-09-28 — — US claimed
EP-4219446-A2 TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES FOR PEPTIDE PURIFICATION Gyros Protein Technologies AB (SE) 2023-08-02 — — EP claimed
CN-116322777-A Heteroaryl and heterocyclyl compounds 西吉隆医疗股份有限公司 2023-06-23 — — CN claimed
EP-4140988-A1 L-VALINATE OF HYDROXYPROPYLTHIAZOLIDINE CARBOXAMIDE DERIVATIVE AND SALT FORM, CRYSTAL POLYMORPH THEREOF Merck Serono S.A. (CH) 2023-03-01 — — EP claimed
US-20230042042-A1 UNNATURAL AMINO ACIDS AND USES THEREOF DEFENSE THREAT REDUCTION AGENCY, US DOD 2023-02-09 — — US claimed
CN-108602762-B Linker molecules and their use in methods for purifying peptides 贝兰迪克有限责任公司 2022-12-16 — — CN claimed
EP-3408257-B1 LINKER MOLECULE AND USE OF IT IN PROCESS FOR PURIFICATION OF PEPTIDES Belyntic GmbH (DE) 2021-12-22 — — EP claimed
US-20210332082-A1 TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES FOR PEPTIDE PURIFICATION Belyntic GmbH (DE) 2021-10-28 — — US claimed
US-20130143251-A1 EXPEDITIOUS SYNTHESIS OF UBIQUITINATED PEPTIDE CONJUGATES BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) 2013-06-06 — — US claimed
EP-2014310-B1 KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy DYAX CORP (US) 2012-10-24 — — EP claimed
EP-2487183-A1 Ubiquitin-isopeptide probes Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2012-08-15 — — EP claimed
WO-2012097860-A1 NOVEL UBIQUITIN-ISOPEPTIDE PROBES Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2012-07-26 — — WO claimed
US-20120184482-A1 Novel Ubiquitin-Isopeptide Probes HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH (DE) 2012-07-19 — — US claimed
US-7666979-B2 polyvalent targeting ligands that bind to cells used for diagnosis of diseases sensitivity to angiogenesis factor BRACCO INTERNATIONAL B.V. (NL) 2010-02-23 — — US claimed
JP-2007529522-A — — 2007-10-25 — — JP claimed
EP-1734994-A1 SITE-SPECIFIC CHEMICAL MODIFICATION OF HIV GP41-DERIVED PEPTIDES Trimeris, Inc. (US) 2006-12-27 — — EP claimed
WO-2005089796-A1 SITE-SPECIFIC CHEMICAL MODIFICATION OF HIV GP41-DERIVED PEPTIDES TRIMERIS, INC. (US) 2005-09-29 — — WO claimed
WO-2003068806-A1 SOLID PHASE PEPTIDE SYNTHESIS ON SILICA JOHNSON MATTHEY PLC (GB) 2003-08-21 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130143251-A1 EXPEDITIOUS SYNTHESIS OF UBIQUITINATED PEPTIDE CONJUGATES UBQLN1, UBQLN2, NEDD4 ALDH1A1 3382/4885MAPT 1755/4885L3MBTL1 2083/4885
US-20230042042-A1 UNNATURAL AMINO ACIDS AND USES THEREOF DNPEP, BCAT2, BCAT1 ALDH1A1 4624/4885MAPT 748/4885L3MBTL1 1398/4885
US-20230303502-A1 HETEROARYL AND HETEROCYCLYL COMPOUNDS CYP3A43, CYP2C9, CYP2C19 ALDH1A1 296/4885MAPT 3042/4885L3MBTL1 4703/4885
US-20120184482-A1 Novel Ubiquitin-Isopeptide Probes USP16, UCHL5, UCHL3 ALDH1A1 1237/4885MAPT 1956/4885L3MBTL1 1757/4885
US-20210332082-A1 TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES FOR PEPTIDE PURIFICATION VIP, NGLY1, HM13 ALDH1A1 1635/4885MAPT 1722/4885L3MBTL1 994/4885
US-20240116981-A1 TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES FOR PEPTIDE PURIFICATION VIP, NGLY1, HM13 ALDH1A1 1725/4885MAPT 1971/4885L3MBTL1 926/4885
US-11884612-B2 Covalent peptide binders PTMS, CD2BP2, CLASP1 ALDH1A1 4419/4885MAPT 1467/4885L3MBTL1 131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.