Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2096469 | 0.86 | ALDH1A1 (0.65) | ALDH1A1TSHRCYP3A4ACHELMNA | |
| SCHEMBL9436732 | 0.82 | ALDH1A1 (0.55) | ALDH1A1TSHRCYP3A4ACHEADRA1A | |
| SCHEMBL30745213 | 0.82 | ALDH1A1 (0.55) | ALDH1A1TSHRCYP3A4ACHEADRA1A | |
| SCHEMBL2504998 | 0.82 | ALDH1A1 (0.55) | ALDH1A1TSHRCYP3A4ACHEADRA1A | |
| SCHEMBL10042839 | 0.82 | TSHR (0.46) | ALDH1A1TSHRACHESIGMAR1MAPT | |
| SCHEMBL6875954 | 0.81 | ACHE (0.48) | ALDH1A1TSHRACHECYP2C19SIGMAR1 | |
| SCHEMBL11594419 | 0.80 | ALDH1A1 (0.53) | ALDH1A1TSHRCYP3A4SIGMAR1HSD17B1 | |
| SCHEMBL619642 | 0.79 | ALDH1A1 (0.52) | ALDH1A1TSHRCYP3A4ACHEADRA1A | |
| SCHEMBL6878932 | 0.79 | ACHE (0.65) | ALDH1A1TSHRCYP3A4ACHECYP2C19 | |
| SCHEMBL11572689 | 0.79 | ALDH1A1 (0.52) | ALDH1A1TSHRCYP3A4ACHEADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10696898-B2 | Reverse photochromic compound | FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) | 2020-06-30 | — | — | US | disclosed |
| US-8163910-B2 | Amide-substituted xanthene dyes | ELITECH HOLDING B.V. (NL) | 2012-04-24 | — | — | US | disclosed |
| US-7767834-B2 | Phosphonylated fluorescent dyes and conjugates | ELITECH HOLDING B.V. (NL) | 2010-08-03 | — | — | US | disclosed |
| US-20090093612-A1 | AMIDE-SUBSTITUTED XANTHENE DYES | EPOCH BIOSCIENCES, INC. (US) | 2009-04-09 | — | — | US | disclosed |
| US-20080207887-A1 | PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES | EPOCH BIOSCIENCES, INC. (US) | 2008-08-28 | — | — | US | disclosed |
| EP-0005451-A2 | Process for the manufacture of cationic oxazinic compounds, the oxazinic compounds and their application to the dyeing and printing of textile materials | CIBA-GEIGY AG (CH) | 1979-11-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207887-A1 | PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES | PHOSPHO1, PFAS, PHPT1 | ALDH1A1 1457/4885TSHR 3676/4885CYP3A4 3508/4885 |
| US-10696898-B2 | Reverse photochromic compound | CRY1, CRY2, C3AR1 | ALDH1A1 840/4885TSHR 1792/4885CYP3A4 683/4885 |
| US-20090093612-A1 | AMIDE-SUBSTITUTED XANTHENE DYES | ANXA5, PHOSPHO1, TPST2 | ALDH1A1 4277/4885TSHR 2157/4885CYP3A4 4043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.