Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21380590 | 0.81 | BCL2 (0.36) | ALOX5CYP1A2BCL2BCL2L1 | |
| SCHEMBL921907 | 0.81 | KEAP1 (0.62) | ENPP2DHFRALOX5DRD2DRD1 | |
| SCHEMBL4651451 | 0.80 | AKR1B1 (0.49) | ENPP2DHFRALOX5CYP3A4 | |
| SCHEMBL3440671 | 0.79 | KEAP1 (0.64) | ALOX5BCL2BCL2L1KMT2AKDM4E | |
| SCHEMBL29279068 | 0.78 | TAAR1 (0.44) | TAAR1 | |
| SCHEMBL7730754 | 0.78 | DHFR (0.54) | ENPP2DHFRALOX5DRD2DRD1 | |
| SCHEMBL29057939 | 0.78 | TAAR1 (0.44) | TAAR1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL38660847 | 0.78 | PNMT (0.47) | TAAR1CYP3A4ALOX15KMT2A | |
| SCHEMBL352619 | 0.78 | CALM1 (0.52) | ALOX5DRD2DRD1BCL2BCL2L1 | |
| SCHEMBL70267 | 0.77 | ENPP2 (0.65) | ENPP2DHFRDRD2DRD1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116239103-B | Carbon dot, preparation method thereof and photocatalytic hydroboration method | 中国石油大学(华东) | 2024-08-02 | — | — | CN | claimed |
| CN-115521324-B | Preparation of near infrared fluorescent probe for detecting beta-lactamase in drug-resistant bacteria | 山西医科大学 | 2023-08-29 | — | — | CN | claimed |
| CN-116239103-A | Carbon dot, preparation method thereof and photocatalytic hydroboration method | 中国石油大学(华东) | 2023-06-09 | — | — | CN | claimed |
| CN-118576786-A | Multifunctional hydrophilic lubricating coating and preparation method thereof | 四川大学华西医院 | 2024-09-03 | — | — | CN | disclosed |
| CN-116239103-B | Carbon dot, preparation method thereof and photocatalytic hydroboration method | 中国石油大学(华东) | 2024-08-02 | — | — | CN | disclosed |
| CN-117304590-B | High-weather-resistance power cable and production process thereof | 荣茂科技集团有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-117304590-A | High-weather-resistance power cable and production process thereof | 荣茂科技集团有限公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-116897195-A | Primer composition for inorganic substance layer lamination, cured product thereof, and method for producing same | 东亚合成株式会社 | 2023-10-17 | — | — | CN | disclosed |
| CN-115521324-B | Preparation of near infrared fluorescent probe for detecting beta-lactamase in drug-resistant bacteria | 山西医科大学 | 2023-08-29 | — | — | CN | disclosed |
| CN-116239103-A | Carbon dot, preparation method thereof and photocatalytic hydroboration method | 中国石油大学(华东) | 2023-06-09 | — | — | CN | disclosed |
| CN-115124837-B | Polyimide composite film | 苏州太湖电工新材料股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| US-8450374-B2 | Pan-antagonists for the androgen receptor and androgen receptor mutants associated with anti-androgen withdrawal | UNIVERSITY OF DELAWARE (US) | 2013-05-28 | — | — | US | disclosed |
| US-20100331418-A1 | Pan-Antagonists For The Androgen Receptor And Androgen Receptor Mutants Associated With Anti-Androgen Withdrawal | UNIVERSITY OF DELAWARE | 2010-12-30 | — | — | US | disclosed |
| US-7807713-B2 | Pan-antagonists for the androgen receptor and androgen associated with anti-androgen withdrawal | UNIVERSITY OF DELAWARE (US) | 2010-10-05 | — | — | US | disclosed |
| US-20090270512-A1 | Pan-Antagonists For The Androgen Receptor And Androgen Receptor Mutants Associated With Anti-Androgen Withdrawal | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-10-29 | — | — | US | disclosed |
| US-7550505-B2 | Pan-antagonists for the androgen receptor and androgen receptor mutants associated with anti-androgen withdrawal | UNIVERSITY OF DELAWARE (US) | 2009-06-23 | — | — | US | disclosed |
| US-7550505-B2 | Pan-antagonists for the androgen receptor and androgen receptor mutants associated with anti-androgen withdrawal | UNIVERSITY OF DELAWARE (US) | 2009-06-23 | — | — | US | disclosed |
| US-20080064757-A1 | Pan-antagonists for the androgen receptor and androgen receptor mutants associated with anti-androgen withdrawal | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-03-13 | — | — | US | disclosed |
| WO-2008013791-A2 | PAN-ANTAGONISTS FOR THE ANDROGEN RECEPTOR AND ANDROGEN RECEPTOR MUTANTS ASSOCIATED WITH ANTI-ANDROGEN WITHDRAWAL | UNIVERSITY OF DELAWARE (US) | 2008-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270512-A1 | Pan-Antagonists For The Androgen Receptor And Androgen Receptor Mutants Associated With Anti-Androgen Withdrawal | AR, NR5A1, SHBG | ENPP2 498/4885DHFR 3793/4885ALOX5 3058/4885 |
| US-20080064757-A1 | Pan-antagonists for the androgen receptor and androgen receptor mutants associated with anti-androgen withdrawal | AR, NR5A1, SHBG | ENPP2 498/4885DHFR 3793/4885ALOX5 3058/4885 |
| US-20100331418-A1 | Pan-Antagonists For The Androgen Receptor And Androgen Receptor Mutants Associated With Anti-Androgen Withdrawal | AR, NR5A1, SHBG | ENPP2 498/4885DHFR 3793/4885ALOX5 3058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.