Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10123566 | 0.81 | POLB (0.44) | L3MBTL1HTTATMMAPK1POLB | |
| SCHEMBL2972774 | 0.81 | L3MBTL1 (0.56) | L3MBTL1HTTATMMAPK1POLB | |
| SCHEMBL2972768 | 0.81 | L3MBTL1 (0.56) | L3MBTL1HTTATMMAPK1POLB | |
| SCHEMBL17331983 | 0.79 | L3MBTL1 (0.58) | L3MBTL1HTTATMMAPK1SMN1; SMN2 | |
| SCHEMBL21240026 | 0.78 | L3MBTL1 (0.56) | L3MBTL1HTTATMMAPK1SMN1; SMN2 | |
| SCHEMBL14910686 | 0.78 | LMNA (0.40) | L3MBTL1HTTATMMAPK1SMN1; SMN2 | |
| SCHEMBL14910325 | 0.77 | KDM4E (0.49) | L3MBTL1HTTATMMAPK1SMN1; SMN2 | |
| SCHEMBL17331425 | 0.77 | ALDH1A1 (0.49) | L3MBTL1HTTATMMAPK1POLB | |
| SCHEMBL21239633 | 0.77 | KDM4E (0.58) | L3MBTL1HTTATMMAPK1SMN1; SMN2 | |
| SCHEMBL1645738 | 0.74 | L3MBTL1 (1.00) | L3MBTL1HTTATMMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983411-B1 | FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS | PI INDUSTRIES LTD (IN) | 2026-05-27 | — | — | EP | disclosed |
| US-12384787-B2 | Fused heterocyclic compounds and their use as pest control agents | PI INDUSTRIES LTD (IN) | 2025-08-12 | — | — | US | disclosed |
| CN-114008043-B | Condensed heterocyclic compounds and their use as pest control agents | PI工业有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-116640135-A | Preparation method of 3-carbonyl-2-fluoro substituted indolizine compound | 平顶山学院 | 2023-08-25 | — | — | CN | disclosed |
| US-20220251094-A1 | FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS | PI INDUSTRIES LTD. (IN) | 2022-08-11 | — | — | US | disclosed |
| EP-3983411-A1 | FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS | PI Industries Ltd. (IN) | 2022-04-20 | — | — | EP | disclosed |
| WO-2020250183-A1 | FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS | PI INDUSTRIES LTD. (IN) | 2020-12-17 | — | — | WO | disclosed |
| US-8748452-B2 | Indolizine derivative and use thereof for medical purposes | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2014-06-10 | — | — | US | disclosed |
| EP-2415771-B1 | INDOLIZINE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | KISSEI PHARMACEUTICAL (JP) | 2013-07-31 | — | — | EP | disclosed |
| EP-2415771-A1 | INDOLIZINE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | Kissei Pharmaceutical Co., Ltd. (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20120015972-A1 | INDOLIZINE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015972-A1 | INDOLIZINE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | XDH, INMT, PON1 | L3MBTL1 785/4885HTT 2283/4885ATM 4343/4885 |
| US-12384787-B2 | Fused heterocyclic compounds and their use as pest control agents | DDT, ACHE, KEAP1 | L3MBTL1 268/4885HTT 1604/4885ATM 2629/4885 |
| US-20220251094-A1 | FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS | DDT, ACHE, KEAP1 | L3MBTL1 268/4885HTT 1604/4885ATM 2629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.