Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34461724 | 0.87 | GRIK1 (0.39) | HCAR1POLBALDH1A1FAAHMGLL | |
| SCHEMBL34461790 | 0.87 | HCAR1 (0.33) | CYP1A2CYP2C19HCAR1ALDH1A1FAAH | |
| SCHEMBL34461760 | 0.85 | GRIA1 (0.32) | HCAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL34461733 | 0.81 | ADORA2A (0.38) | CYP1A2CYP2C19HCAR1MAPTPOLB | |
| SCHEMBL34461723 | 0.78 | TRPA1 (0.42) | CYP1A2CYP2C19MAPTPOLBALDH1A1 | |
| SCHEMBL34461734 | 0.69 | ALDH1A1 (0.36) | CYP1A2CYP2C19HCAR1MAPTALDH1A1 | |
| SCHEMBL34461744 | 0.69 | ALDH1A1 (0.37) | CYP1A2CYP2C19ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL34461729 | 0.68 | ALDH1A1 (0.35) | ALDH1A1KMT2A | |
| SCHEMBL34461739 | 0.65 | TRPA1 (0.43) | MAPTPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL5661381 | 0.59 | ALDH1A1 (0.44) | HCAR1ALDH1A1FAAHMGLLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260098041-A1 | FUSED BICYCLIC PYRIMIDONES AS WRN INHIBITORS | INCYTE CORPORATION (US) | 2026-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260098041-A1 | FUSED BICYCLIC PYRIMIDONES AS WRN INHIBITORS | WRN, POLR1A, REV1 | CYP1A2 3621/4885CYP2C19 3664/4885HCAR1 848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.