Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.31 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34461733 | 0.88 | ADORA2A (0.38) | ALDH1A1ADORA2AHCAR1HTTLMNA | |
| SCHEMBL34461744 | 0.87 | ALDH1A1 (0.37) | ALDH1A1ADORA2AHTTLMNACYP1A2 | |
| SCHEMBL34461790 | 0.82 | HCAR1 (0.33) | ALDH1A1KMT2AHCAR1CYP1A2CYP3A4 | |
| SCHEMBL34461729 | 0.82 | ALDH1A1 (0.35) | ALDH1A1KMT2AADORA2ALMNA | |
| SCHEMBL34461722 | 0.79 | TRPA1 (0.43) | ALDH1A1KMT2AHTTCYP1A2CYP3A4 | |
| SCHEMBL34461772 | 0.69 | CYP1A2 (0.35) | ALDH1A1KMT2AHCAR1CYP1A2CYP3A4 | |
| SCHEMBL34461724 | 0.69 | GRIK1 (0.39) | ALDH1A1KMT2AHCAR1FAAHMGLL | |
| SCHEMBL34461787 | 0.65 | ADORA2A (0.42) | ALDH1A1KMT2AADORA2AGAAMAPT | |
| SCHEMBL34461760 | 0.64 | GRIA1 (0.32) | ALDH1A1KMT2AHCAR1 | |
| SCHEMBL31213128 | 0.62 | ALDH1A1 (0.61) | ALDH1A1KMT2AHCAR1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260098041-A1 | FUSED BICYCLIC PYRIMIDONES AS WRN INHIBITORS | INCYTE CORPORATION (US) | 2026-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260098041-A1 | FUSED BICYCLIC PYRIMIDONES AS WRN INHIBITORS | WRN, POLR1A, REV1 | ALDH1A1 1354/4885KMT2A 3313/4885ADORA2A 586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.