SCHEMBL345537

SCHEMBL345537

CCCC(Cc1ccccc1)(C(=O)c1ccc(N2CCOCC2)cc1)N(CC)CC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.46
MAOB P27338 1/20 0.44
ESR1 P03372 1/20 0.43
MAPT P10636 6/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
LMNA P02545 1/20 0.43
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
ALDH1A1 P00352 3/20 0.41
RAB9A P51151 2/20 0.41
NPC1 O15118 1/20 0.41
GSK3B P49841 1/20 0.41
SLC13A5 Q86YT5 1/20 0.39
RORC P51449 1/20 0.39
PIK3CD O00329 1/20 0.38
PIK3CA P42336 1/20 0.38
PIK3CB P42338 1/20 0.38
PIK3CG P48736 1/20 0.38
PRKDC P78527 1/20 0.38
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pentanal SCHEMBL28914405 0.92 ESR1 (0.42) SMN1; SMN2MAOBESR1MAPTL3MBTL1
SCHEMBL1781930 0.91 SMN1; SMN2 (0.47) SMN1; SMN2MAOBESR1MAPTL3MBTL1
SCHEMBL8900259 0.90 SMN1; SMN2 (0.46) SMN1; SMN2MAOBESR1MAPTL3MBTL1
SCHEMBL27853188 0.85 SMN1; SMN2 (0.44) SMN1; SMN2MAOBESR1MAPTL3MBTL1
SCHEMBL8898916 0.84 SMN1; SMN2 (0.51) SMN1; SMN2MAOBESR1MAPTL3MBTL1
SCHEMBL29276587 0.84 ALDH1A1 (0.44) SMN1; SMN2MAPTL3MBTL1LMNAMEN1
SCHEMBL8898042 0.84 SMN1; SMN2 (0.45) SMN1; SMN2MAOBESR1MAPTL3MBTL1
SCHEMBL27835170 0.84 ALDH1A1 (0.46) SMN1; SMN2ESR1MAPTL3MBTL1LMNA
SCHEMBL10226595 0.84 SMN1; SMN2 (0.46) SMN1; SMN2MAOBESR1MAPTL3MBTL1
SCHEMBL28990186 0.84 SMN1; SMN2 (0.48) SMN1; SMN2MAOBESR1MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4725470-A1 CURABLE DENTAL COMPOSITION Kuraray Noritake Dental Inc. (JP) 2026-04-15 EP disclosed
EP-4613256-A1 DENTAL ADHESIVE COMPOSITION Kuraray Noritake Dental Inc. (JP) 2025-09-10 EP disclosed
US-20250186309-A1 DENTAL CURABLE COMPOSITION AND DENTAL KIT KURARAY NORITAKE DENTAL INC. (JP) 2025-06-12 US disclosed
US-20250032366-A1 DENTAL CURABLE COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2025-01-30 US disclosed
EP-3646847-B1 TWO-PASTE TYPE DENTAL CURABLE COMPOSITION KURARAY NORITAKE DENTAL INC (JP) 2025-01-29 EP disclosed
US-20250000747-A1 SEPARATE-PACK TYPE DENTAL CURABLE COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2025-01-02 US disclosed
WO-2024253204-A1 CURABLE DENTAL COMPOSITION クラレノリタケデンタル株式会社 2024-12-12 WO disclosed
EP-4445891-A1 DENTAL CURABLE COMPOSITION Kuraray Noritake Dental Inc. (JP) 2024-10-16 EP disclosed
US-20240315930-A1 PASTE-FORM TWO-PACK TYPE DENTAL CURABLE COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2024-09-26 US disclosed
US-20240315929-A1 DENTAL ADHESIVE KIT KURARAY NORITAKE DENTAL INC. (JP) 2024-09-26 US disclosed
US-20090068123-A1 FLUORINE ION-RELEASABLE COMPOSITION FOR DENTAL PURPOSES KURARAY MEDICAL INC (JP) 2009-03-12 US disclosed
EP-1864645-A1 FLUORINE ION-RELEASABLE COMPOSITION FOR DENTAL PURPOSES Kuraray Medical Inc. (JP) 2007-12-12 EP disclosed
US-20060078510-A1 Dental coating kit KURARAY MEDICAL INC. (JP) 2006-04-13 US disclosed
EP-1550428-A1 DENTAL COATING KIT Kuraray Medical Inc. (JP) 2005-07-06 EP disclosed
US-6759449-B2 NONCROSSLINKING POLYMETHYL METHACRYLATE AND POLYETHYL METH-ACRYLATE SPHERICAL FILLER, UNSATURATED ACID FUNCTIONALIZED MONOMER AND POLYMERIZATION INITIATOR TOKUYAMA DENTAL CORPORATION (JP) 2004-07-06 US disclosed
US-20030050359-A1 Dental adhesive composition TOKUYAMA DENTAL CORPORATION (JP) 2003-03-13 US disclosed
EP-1249221-A1 DENTAL ADHESIVE COMPOSITION Tokuyama Dental Corporation (JP) 2002-10-16 EP disclosed
EP-0712622-B1 Dental composition and kit TOKUYAMA CORP (JP) 1999-09-01 EP disclosed
US-5925690-A UNSATURATED PHOSPHATE AND UNSATURATED POLYCARBOXYLIC ACID MONOMERS; BONDING AND TENSILE STRENGTH TO DENTIN AND ENAMEL TOKUYAMA CORPROATION (JP) 1999-07-20 US disclosed
EP-0712622-A1 Dental composition and kit TOKUYAMA CORPORATION (JP) 1996-05-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250000747-A1 SEPARATE-PACK TYPE DENTAL CURABLE COMPOSITION CAD, CCDC6, CALCOCO2 SMN1; SMN2 2353/4885MAOB 787/4885ESR1 3220/4885
US-20240315930-A1 PASTE-FORM TWO-PACK TYPE DENTAL CURABLE COMPOSITION TIPRL, STAU1, CALCOCO2 SMN1; SMN2 1747/4885MAOB 2611/4885ESR1 4413/4885
US-20250032366-A1 DENTAL CURABLE COMPOSITION H1-0, COL1A1, CHAF1B SMN1; SMN2 3223/4885MAOB 1971/4885ESR1 4417/4885
US-20090068123-A1 FLUORINE ION-RELEASABLE COMPOSITION FOR DENTAL PURPOSES ITGA5, ITGAL, PHOSPHO1 SMN1; SMN2 996/4885MAOB 3763/4885ESR1 908/4885
US-20030050359-A1 Dental adhesive composition CAD, ASIC1, CD44 SMN1; SMN2 3961/4885MAOB 4157/4885ESR1 3453/4885
US-20250186309-A1 DENTAL CURABLE COMPOSITION AND DENTAL KIT KIT, DNMT3L, CDK6 SMN1; SMN2 1275/4885MAOB 4158/4885ESR1 2198/4885
US-20240315929-A1 DENTAL ADHESIVE KIT ITGA1, CAD, ITGA2 SMN1; SMN2 3797/4885MAOB 2817/4885ESR1 1967/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.