Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3457811 | 0.80 | OPRD1 (0.45) | — | |
| Hydrochloric Acid SCHEMBL8564106 | 0.80 | ADRA1D (0.37) | ADRA1DNR3C2 | |
| SCHEMBL7843937 | 0.72 | NR3C1 (0.36) | ADRA1DNR3C2NR3C1PGRALDH1A1 | |
| Hydrochloric Acid SCHEMBL7366379 | 0.71 | GHSR (0.42) | SMN1; SMN2 | |
| SCHEMBL9034360 | 0.71 | KCNH2 (0.37) | ALDH1A1 | |
| Sulfuric Acid SCHEMBL9032305 | 0.71 | KCNH2 (0.35) | SMN1; SMN2 | |
| SCHEMBL4707460 | 0.70 | ALOX15 (0.40) | NR3C1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL2589311 | 0.70 | OPRD1 (0.44) | ALDH1A1 | |
| SCHEMBL267585 | 0.70 | ADRA1D (0.56) | ADRA1D | |
| Hydrochloric Acid SCHEMBL261711 | 0.69 | ADRA1D (0.55) | ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2255201-A2 | FLUORESCENCE POLARIZATION HERG ASSAY | Life Technologies Corporation (US) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009108905-A2 | FLUORESCENCE POLARIZATION HERG ASSAY | Life Technologies Corporation (US) | 2009-09-03 | — | — | WO | disclosed |