SCHEMBL3468376

SCHEMBL3468376

CC(=COCCOc1ccccc1)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
KDM4E B2RXH2 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
PKM P14618 2/20 0.50
MTNR1A P48039 1/20 0.50
MTNR1B P49286 1/20 0.50
RAB9A P51151 3/20 0.49
THRB P10828 1/20 0.49
MAPT P10636 1/20 0.49
PARP10 Q53GL7 1/20 0.47
ALDH1A1 P00352 3/20 0.46
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
RECQL P46063 2/20 0.44
NPC1 O15118 2/20 0.44
TSHR P16473 1/20 0.44
KCNA3 P22001 1/20 0.44
LMNA P02545 1/20 0.44
ALOX15 P16050 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9750805 0.92 L3MBTL1 (0.51) SMN1; SMN2L3MBTL1KDM4ETDP1PKM
SCHEMBL17825824 0.81 RECQL (0.48) SMN1; SMN2L3MBTL1KDM4ETDP1PKM
SCHEMBL28506569 0.80 PTGS1 (0.33) SMN1; SMN2L3MBTL1KDM4ETDP1
SCHEMBL28193352 0.79 THRB (0.49) SMN1; SMN2L3MBTL1KDM4ETDP1PKM
SCHEMBL23244074 0.78 L3MBTL1 (0.50) SMN1; SMN2L3MBTL1KDM4ETDP1PKM
SCHEMBL1901807 0.78 ALDH1A1 (0.47) SMN1; SMN2L3MBTL1TDP1RAB9AALDH1A1
SCHEMBL196481 0.78 MTNR1A (0.51) SMN1; SMN2L3MBTL1KDM4ETDP1PKM
SCHEMBL23244076 0.78 L3MBTL1 (0.50) SMN1; SMN2L3MBTL1KDM4ETDP1PKM
SCHEMBL15256 0.78 MTNR1A (0.51) SMN1; SMN2L3MBTL1KDM4ETDP1PKM
Methacrylic Acid SCHEMBL1350759 0.77 PKM (0.58) SMN1; SMN2L3MBTL1KDM4ETDP1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008079519-A1 PHOTOSENSITIVE COMPOSITION WITH LOW YELLOWING UNDER UV-LIGHT AND SUNLIGHT EXPOSURE CLAST TRADING LIMITED (CN) 2008-07-03 WO claimed
US-20070099119-A1 Photosensitive composition with low yellowing under UV-light and sunlight exposure CHEMENCE, INC. 2007-05-03 US claimed
US-5021467-A Polycarbonates modified by 6-hydoxycaproic acid and an acrylic acid, unsaturated compound and a photoinitiator; quick setting coatings of optical glass fibers NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1991-06-04 US claimed
US-8889338-B2 Flexographic printing forme precursor for laser engraving AGFA GRAPHICS NV (BE) 2014-11-18 US disclosed
US-8268533-B2 Flexographic printing forme precursor for laser engraving AGFA GRAPHICS NV (BE) 2012-09-18 US disclosed
US-20120213984-A1 FLEXOGRAPHIC PRINTING FORME PRECURSOR FOR LASER ENGRAVING AGFA GRAPHICS NV (BE) 2012-08-23 US disclosed
EP-1936438-B1 Flexographic printing forme precursor for laser engraving AGFA GRAPHICS NV (BE) 2010-03-10 EP disclosed
US-20100009285-A1 FLEXOGRAPHIC PRINTING FORME PRECURSOR FOR LASER ENGRAVING AGFA GRAPHICS NV (BE) 2010-01-14 US disclosed
WO-2008074796-A1 FLEXOGRAPHIC PRINTING FORME PRECURSOR FOR LASER ENGRAVING AGFA GRAPHICS NV (BE) 2008-06-26 WO disclosed
EP-1936438-A1 Flexographic printing forme precursor for laser engraving Agfa Graphics N.V. (BE) 2008-06-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120213984-A1 FLEXOGRAPHIC PRINTING FORME PRECURSOR FOR LASER ENGRAVING ESD, FMNL1, FEM1B SMN1; SMN2 695/4885L3MBTL1 1285/4885KDM4E 227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.