Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | GLB1 | P16278 | 1/20 | 0.50 |
| ▸ | CTRC | Q99895 | 1/20 | 0.50 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.50 |
| ▸ | DHFR | P00374 | 5/20 | 0.39 |
| ▸ | TYMS | P04818 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5146060 | 0.89 | HPGD (0.50) | THRBRECQLTDP1ALDH1A1MEN1 | |
| SCHEMBL8034668 | 0.86 | TDP1 (0.45) | THRBRECQLTDP1ALDH1A1MEN1 | |
| SCHEMBL204164 | 0.82 | ALDH1A1 (0.48) | THRBRECQLTDP1ALDH1A1MEN1 | |
| SCHEMBL202598 | 0.82 | ALDH1A1 (0.48) | THRBRECQLTDP1ALDH1A1MEN1 | |
| SCHEMBL29024627 | 0.81 | THRB (0.72) | THRBRECQLTDP1ALDH1A1MEN1 | |
| SCHEMBL18171688 | 0.80 | ALDH1A1 (0.44) | THRBRECQLTDP1ALDH1A1MEN1 | |
| SCHEMBL1689593 | 0.77 | ALDH1A1 (0.44) | THRBRECQLTDP1ALDH1A1MEN1 | |
| SCHEMBL29486978 | 0.77 | MEN1 (0.61) | THRBRECQLTDP1ALDH1A1MEN1 | |
| SCHEMBL498286 | 0.77 | MEN1 (0.61) | THRBRECQLTDP1ALDH1A1MEN1 | |
| SCHEMBL12836277 | 0.76 | THRB (0.36) | THRBRECQLTDP1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011850-A2 | AMPLIFICATION ASSAY FOR THE DETECTION OF ANAPLASMA PHAGOCYTOPHILUM | CHAO CHIEN CHUNG (US) | 2021-01-21 | — | — | WO | claimed |
| WO-2017124054-A1 | METHODS AND REAGENTS FOR DETECTION OF CHIKUNGUNYA VIRUS AND ZIKA VIRUS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2017-07-20 | — | — | WO | claimed |
| US-9587271-B2 | Mixtures for assaying nucleic acid, novel method of assaying nucleic acid with the use of the same and nucleic acid probe to be used therefor | NIPPON STEEL & SUMIKIN ECO-TECH CORPORATION (JP) | 2017-03-07 | — | — | US | claimed |
| EP-2904120-A1 | METHODS AND REAGENTS FOR DETECTION, QUANTITATION, AND SEROTYPING OF DENGUE VIRUSES | The Board of Trustees of The Leland Stanford Junior University (US) | 2015-08-12 | — | — | EP | claimed |
| WO-2014055746-A1 | METHODS AND REAGENTS FOR DETECTION, QUANTITATION, AND SEROTYPING OF DENGUE VIRUSES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2014-04-10 | — | — | WO | claimed |
| US-8551706-B2 | Identification of oligonucleotides for the capture, detection and quantitation of West Nile Virus | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2013-10-08 | — | — | US | claimed |
| EP-1552022-B1 | IDENTIFICATION OF OLIGONUCLEOTIDES FOR THE CAPTURE, DETECTION AND QUANTITATION OF HEPATITIS A VIRAL NUCLEIC ACID | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2013-01-23 | — | — | EP | claimed |
| US-20120219941-A1 | Identification of Oligonucleotides for the Capture, Detection and Quantitation of Hepatitis A Viral Nucleic Acid | CHIRON CORPORATION | 2012-08-30 | — | — | US | claimed |
| US-20120015345-A1 | Identification of Oligonucleotides for the Capture, Detection and Quantitation of West Nile Virus | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2012-01-19 | — | — | US | claimed |
| US-20110150911-A1 | Methods and reagents for treating, preventing and diagnosing bunyavirus infection | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2011-06-23 | — | — | US | claimed |
| US-20070128637-A1 | Identification of oligonucleotides for the capture, detection and quantitation of West Nile virus | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2007-06-07 | — | — | US | claimed |
| US-20050032729-A1 | Identification of oligonucleotides for the capture, detection and quantitation of West Nile virus | CHIRON CORPORATION | 2005-02-10 | — | — | US | claimed |
| US-20030175698-A1 | Retrovirus-specific oligonucleotides and a method for measuring retroviral titer using same | VIROMED, CO., LTD. (KR) | 2003-09-18 | — | — | US | claimed |
| US-20030143527-A1 | Identification of oligonucleotides for the capture, detection and quantitation of hepatitis B viral DNA | SHYAMALA VENKATAKRISHNA (US) | 2003-07-31 | — | — | US | claimed |
| WO-2002090587-A1 | RETROVIRUS-SPECIFIC OLIGONUCLEOTIDES AND A METHOD FOR MEASURING RETROVIRAL TITER USING SAME | VIROMED CO., LTD. (KR) | 2002-11-14 | — | — | WO | claimed |
| EP-0904411-B1 | PASSIVE INTERNAL REFERENCES FOR THE DETECTION OF NUCLEIC ACID AMPLIFICATION PRODUCTS | PE CORP NY (US) | 2001-11-14 | — | — | EP | claimed |
| US-6180349-B1 | AMPLIFICATION; CALIBRATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2001-01-30 | — | — | US | claimed |
| EP-0904411-A1 | PASSIVE INTERNAL REFERENCES FOR THE DETECTION OF NUCLEIC ACID AMPLIFICATION PRODUCTS | The Perkin-Elmer Corporation (US) | 1999-03-31 | — | — | EP | claimed |
| US-5736333-A | INTERNAL REFERENCE MOLECULE COMPRISING FIRST AND SECOND FLUOROPHORES JOINED BY NONHYBRIDIZING BACKBONE CONNECTOR WHICH PERMITS THE TRANSFER OF ENERGY FROM ONE TO THE OTHER | THE PERKIN-ELMER CORPORATION (US) | 1998-04-07 | — | — | US | claimed |
| WO-1997046708-A1 | PASSIVE INTERNAL REFERENCES FOR THE DETECTION OF NUCLEIC ACID AMPLIFICATION PRODUCTS | THE PERKIN-ELMER CORPORATION (US) | 1997-12-11 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110150911-A1 | Methods and reagents for treating, preventing and diagnosing bunyavirus infection | HAVCR2, MME, LGMN | THRB 4405/4885RECQL 2121/4885TDP1 3470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.