Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | THRB | P10828 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | GLB1 | P16278 | 1/20 | 0.48 |
| ▸ | CTRC | Q99895 | 1/20 | 0.48 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL202598 | 0.91 | ALDH1A1 (0.48) | ALDH1A1THRBRECQLTDP1HPGD | |
| SCHEMBL8359568 | 0.87 | TDP1 (0.43) | ALDH1A1THRBRECQLTDP1HPGD | |
| SCHEMBL5094500 | 0.87 | THRB (0.41) | ALDH1A1THRBRECQLTDP1HPGD | |
| SCHEMBL18171688 | 0.85 | ALDH1A1 (0.44) | ALDH1A1THRBRECQLTDP1HPGD | |
| SCHEMBL3472516 | 0.85 | THRB (0.44) | ALDH1A1THRBRECQLTDP1HPGD | |
| SCHEMBL347626 | 0.82 | THRB (0.50) | ALDH1A1THRBRECQLTDP1HPGD | |
| SCHEMBL1022908 | 0.81 | SMAD3 (0.40) | ALDH1A1THRBRECQLTDP1HPGD | |
| SCHEMBL7589676 | 0.79 | SMAD3 (0.37) | ALDH1A1THRBRECQLTDP1HPGD | |
| SCHEMBL229962 | 0.78 | ALDH1A1 (0.43) | ALDH1A1THRBRECQLTDP1HPGD | |
| SCHEMBL5665945 | 0.78 | ALDH1A1 (0.58) | ALDH1A1THRBRECQLTDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116589475-B | Preparation method of 2',4',5',7' -tetrachloro-5 (6) -carboxyl-4, 7-dichloro fluorescein | 北京欧凯纳斯生化科技有限公司 | 2023-09-29 | — | — | CN | claimed |
| CN-116589475-A | Preparation method of 2',4',5',7' -tetrachloro-5 (6) -carboxyl-4, 7-dichloro fluorescein | 北京欧凯纳斯生化科技有限公司 | 2023-08-15 | — | — | CN | claimed |
| EP-2371927-B1 | Fluorescent dye compounds, conjugates and uses thereof | LIFE TECHNOLOGIES CORP (US) | 2020-03-11 | — | — | EP | claimed |
| US-9110075-B2 | Compositions for analyzing proteins | MONOGRAM BIOSCIENCES, INC. (US) | 2015-08-18 | — | — | US | claimed |
| US-8729267-B2 | Fluorescent dye compounds, conjugates and uses thereof | APPLIED BIOSYSTEMS, LLC (US) | 2014-05-20 | — | — | US | claimed |
| US-20130122506-A1 | NUCLEIC ACID BASE ANALOGS WITH QUENCHING AND FLUORESCENT ACTIVITIES AND APPLICATIONS THEREOF | TAGCYX BIOTECHNOLOGIES C/O RIKEN (JP) | 2013-05-16 | — | — | US | claimed |
| EP-2562255-A1 | NUCLEIC ACID BASE ANALOG WITH QUENCHING CHARACTERISTICS AND FLUORESCENCE AND APPLICATION THEREOF | Riken (JP) | 2013-02-27 | — | — | EP | claimed |
| US-8212014-B2 | Artificial base pairs and uses thereof | RIKEN (JP) | 2012-07-03 | — | — | US | claimed |
| US-20110250699-A1 | Fluorescent Dye Compounds, Conjugates and Uses Thereof | Life Technologies Corporation (US) | 2011-10-13 | — | — | US | claimed |
| EP-2371927-A1 | Fluorescent dye compounds, conjugates and uses thereof | Life Technologies Corporation (US) | 2011-10-05 | — | — | EP | claimed |
| US-20090275017-A1 | Novel Nucleoside or Nucleotide Derivative and Use Thereof | RIKEN (JP) | 2009-11-05 | — | — | US | claimed |
| US-20090093062-A1 | Fluorescent Dye Compounds, Conjugates and Uses Thereof | APPLERA CORPORATION (US) | 2009-04-09 | — | — | US | claimed |
| EP-1921141-A1 | NOVEL ARTIFICIAL BASE PAIR AND USE THEREOF | Riken (JP) | 2008-05-14 | — | — | EP | claimed |
| EP-1816130-A1 | NOVEL NUCLEOSIDE OR NUCLEOTIDE DERIVATIVE AND USE THEREOF | Riken (JP) | 2007-08-08 | — | — | EP | claimed |
| US-20060063734-A1 | 4,7-dichlorofluorescein dyes as molecular probes | APPLERA CORPORATION (US) | 2006-03-23 | — | — | US | claimed |
| US-20050084870-A1 | 4,7-dichlorofluorescein dyes as molecular probes | APPLERA CORPORATION (US) | 2005-04-21 | — | — | US | claimed |
| EP-0777749-B1 | COUPLED AMPLIFICATION AND LIGATION METHOD | PE CORP NY (US) | 2002-10-30 | — | — | EP | claimed |
| US-20020081616-A1 | 4,7-dichlorofluorescein dyes as molecular probes | THE PERKIN-ELMER CORPORATION | 2002-06-27 | — | — | US | claimed |
| US-6130073-A | DETECTING A TARGET NUCLEOTIDE SEQUENCES IN A SAMPLE; AMPLIFYING TARGET NUCLEOTIDE SEQUENCES BY PRIMER EXTENSION, LIGATING OLIGONUCLEOTIDE PROBES AND DETECTING LIGATION PRODUCTS | PERKIN-ELMER CORP., APPLIED BIOSYSTEMS DIVISION (US) | 2000-10-10 | — | — | US | claimed |
| US-5912148-A | DETECTION OF POLYNUCLEOTIDE IN SAMPLE BY POLYMERASE CHAIN REACTION AND LIGATION OF OLIGONUCLEOTIDE PROBES WHICH HYBRIDIZE TO AMPLIFICATION PRODUCT, DETECTION OF LIGATION PRODUCT IN ONE REACTION VESSEL | PERKIN-ELMER CORPORATION APPLIED BIOSYSTEMS (US) | 1999-06-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275017-A1 | Novel Nucleoside or Nucleotide Derivative and Use Thereof | DUT, NT5C3B, NT5C | ALDH1A1 2280/4885THRB 1826/4885RECQL 194/4885 |
| US-20060063734-A1 | 4,7-dichlorofluorescein dyes as molecular probes | SPAG5, SPG11, SPIN4 | ALDH1A1 795/4885THRB 4221/4885RECQL 193/4885 |
| US-20050084870-A1 | 4,7-dichlorofluorescein dyes as molecular probes | DCLRE1B, DCTD, DDB1 | ALDH1A1 405/4885THRB 3306/4885RECQL 226/4885 |
| US-20020081616-A1 | 4,7-dichlorofluorescein dyes as molecular probes | SPAG5, SPG11, SPIN4 | ALDH1A1 658/4885THRB 4266/4885RECQL 202/4885 |
| US-20090093062-A1 | Fluorescent Dye Compounds, Conjugates and Uses Thereof | GFPT1, SLC46A1, SLC7A5 | ALDH1A1 146/4885THRB 4151/4885RECQL 1662/4885 |
| US-20110250699-A1 | Fluorescent Dye Compounds, Conjugates and Uses Thereof | GFPT1, SLC46A1, SLC7A5 | ALDH1A1 146/4885THRB 4151/4885RECQL 1662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.