SCHEMBL3476767

SCHEMBL3476767

CC(CCCN=C=O)(O[SiH3])c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.31
MAPK1 P28482 1/20 0.31
KCNH2 Q12809 1/20 0.31
CYP2C19 P33261 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3481672 0.76 MAPK1 (0.38) KIF11MAPK1
SCHEMBL5180283 0.76 MAPK1 (0.38) KIF11MAPK1
SCHEMBL985309 0.72
SCHEMBL3481487 0.72 MAPK1 (0.40) MAPK1CYP2C19HIF1A
SCHEMBL13133310 0.72 KIF11 (0.34) KIF11
SCHEMBL11152541 0.72 KIF11 (0.34) KIF11
SCHEMBL7598482 0.71 MIF (0.33) KIF11
SCHEMBL11645063 0.71 EBP (0.41) KIF11
SCHEMBL29106963 0.70 NAAA (0.35) KIF11
SCHEMBL3808161 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112142945-B High-stability silyl-terminated polymer resin and preparation method thereof 万华化学集团股份有限公司 2022-07-12 CN claimed
EP-2069415-B1 PROCESS FOR PREPARING A CURABLE SILYLATED POLYURETHANE RESIN MOMENTIVE PERFORMANCE MAT INC (US) 2021-04-21 EP claimed
CN-107406570-B Silylated polyurethanes, their preparation and use 汉高股份有限及两合公司 2021-02-19 CN claimed
CN-112142945-A High-stability silyl-terminated polymer resin and preparation method thereof 万华化学集团股份有限公司 2020-12-29 CN claimed
US-20190031812-A1 Silylated Polyurethanes, Their Preparation and Use HENKEL AG & CO. KGAA (DE) 2019-01-31 US claimed
US-10118984-B2 Silylated polyurethanes, their preparation and use HENKEL AG & CO. KGAA (DE) 2018-11-06 US claimed
US-20170362371-A1 Silylated Polyurethanes, Their Preparation and Use HENKEL AG & CO. KGAA (DE) 2017-12-21 US claimed
EP-3067375-B1 SILYLATED POLYURETHANES, THEIR PREPARATION AND USE HENKEL AG & CO KGAA (DE) 2017-08-30 EP claimed
WO-2016142416-A1 SILYLATED POLYURETHANES, THEIR PREPARATION AND USE HENKEL AG & CO. KGAA (DE) 2016-09-15 WO claimed
EP-3067375-A1 SILYLATED POLYURETHANES, THEIR PREPARATION AND USE Henkel AG & Co. KGaA (DE) 2016-09-14 EP claimed
EP-1885731-B1 PROCESS FOR THE PRODUCTION OF ISOCYANATOSILANE AND SILYLISOCYANURATE MOMENTIVE PERFORMANCE MAT INC (US) 2009-11-11 EP claimed
EP-2069415-A1 PROCESS FOR PREPARING A CURABLE SILYLATED POLYURETHANE RESIN Momentive Performance Materials Inc. (US) 2009-06-17 EP claimed
EP-1937697-A2 METHOD FOR PRODUCTION OF ISOCYANATOSILANES Momentive Performance Materials Inc. (US) 2008-07-02 EP claimed
WO-2008036364-A1 PROCESS FOR PREPARING A CURABLE SILYLATED POLYURETHANE RESIN MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-03-27 WO claimed
US-20080076899-A1 Process for preparing a curable silylated polyurethane resin GENERAL ELECTRIC COMPANY (US) 2008-03-27 US claimed
EP-1885731-A1 PROCESS FOR THE PRODUCTION OF ISOCYANATOSILANE AND SILYLISOCYANURATE Momentive Performance Materials Inc. (US) 2008-02-13 EP claimed
WO-2007037817-A2 METHOD FOR PRODUCTION OF ISOCYANATOSILANES MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2007-04-05 WO claimed
WO-2006132799-A1 PROCESS FOR THE PRODUCTION OF ISOCYANATOSILANE AND SILYLISOCYANURATE MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2006-12-14 WO claimed
US-20060276644-A1 Process for the production of isocyanatosilane and silylisocyanurate GENERAL ELECTRIC COMPANY 2006-12-07 US claimed
US-7060849-B1 Method for production of isocyanatosilanes GENERAL ELECTRIC COMPANY (US) 2006-06-13 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060276644-A1 Process for the production of isocyanatosilane and silylisocyanurate SI, TST, PCMT1 KIF11 2160/4885MAPK1 2180/4885KCNH2 1891/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.