Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 6/20 | 0.39 |
| ▸ | PPARD | Q03181 | 6/20 | 0.39 |
| ▸ | PPARA | Q07869 | 6/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15445476 | 0.93 | ALDH1A1 (0.55) | GPR84FFAR1FFAR4ALDH1A1TSHR | |
| SCHEMBL6550919 | 0.91 | ALDH1A1 (0.52) | GPR84FFAR1FFAR4ALDH1A1TSHR | |
| SCHEMBL1498093 | 0.89 | ACHE (0.46) | ALDH1A1TSHR | |
| SCHEMBL536456 | 0.89 | ACHE (0.46) | ALDH1A1TSHR | |
| SCHEMBL1498116 | 0.89 | ACHE (0.46) | ALDH1A1TSHR | |
| SCHEMBL3846617 | 0.89 | ACHE (0.46) | ALDH1A1TSHR | |
| SCHEMBL3482971 | 0.89 | ACHE (0.46) | ALDH1A1TSHR | |
| SCHEMBL6060295 | 0.87 | ACHE (0.43) | ALDH1A1 | |
| SCHEMBL26381199 | 0.87 | FFAR1 (0.52) | GPR84FFAR1FFAR4ALDH1A1CAMK2A | |
| Palmitic Acid SCHEMBL27753195 | 0.86 | GPR84 (0.59) | GPR84FFAR1FFAR4ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130345260-A1 | High Viscosity Liquid Controlled Delivery System and Medical or Surgical Device | DURECT CORPORATION (US) | 2013-12-26 | — | — | US | disclosed |
| US-7833543-B2 | Sustained release of active materials; storage stability | DURECT CORPORATION (US) | 2010-11-16 | — | — | US | disclosed |
| US-20080152708-A1 | High viscosity liquid controlled delivery system and medical or surgical device | DURECT CORPORATION | 2008-06-26 | — | — | US | disclosed |
| US-20080145419-A1 | High viscosity liquid controlled delivery system and medical or surgical device | DURECT CORPORATION | 2008-06-19 | — | — | US | disclosed |
| US-20060210599-A1 | Injectable or sprayable nonpolymeric ester or mixed ester solution easily formulated with therapeutic agents | GIBSON JOHN W | 2006-09-21 | — | — | US | disclosed |
| US-7053209-B1 | High viscosity liquid controlled delivery system and medical or surgical device | DURECT CORPORATION (US) | 2006-05-30 | — | — | US | disclosed |
| EP-1212092-B1 | HIGH VISCOSITY LIQUID CONTROLLED DELIVERY SYSTEM AND MEDICAL OR SURGICAL DEVICE | DURECT CORP (US) | 2005-10-26 | — | — | EP | disclosed |
| WO-2004052336-A2 | HIGH VISCOSITY LIQUID CONTROLLED DELIVERY SYSTEM AND MEDICAL OR SURGICAL DEVICE | DURECT CORPORATION (US) | 2004-06-24 | — | — | WO | disclosed |
| US-20040101557-A1 | High viscosity liquid controlled delivery system and medical or surgical device | DURECT CORPORATION | 2004-05-27 | — | — | US | disclosed |
| US-6413536-B1 | DELIVERING ACTIVE MATERIALS | SOUTHERN BIOSYSTEMS, INC. | 2002-07-02 | — | — | US | disclosed |
| EP-1212092-A2 | HIGH VISCOSITY LIQUID CONTROLLED DELIVERY SYSTEM AND MEDICAL OR SURGICAL DEVICE | Southern Biosystems, Inc. (US) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001015734-A2 | HIGH VISCOSITY LIQUID CONTROLLED DELIVERY SYSTEM AND MEDICAL OR SURGICAL DEVICE | SOUTHERN BIOSYSTEMS, INC. (US) | 2001-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060210599-A1 | Injectable or sprayable nonpolymeric ester or mixed ester solution easily formulated with therapeutic agents | MMP1, MMP11, MMP13 | GPR84 1897/4885FFAR1 1550/4885FFAR4 1303/4885 |
| US-20080152708-A1 | High viscosity liquid controlled delivery system and medical or surgical device | MMP1, MMP13, MMP9 | GPR84 2110/4885FFAR1 4101/4885FFAR4 4370/4885 |
| US-20040101557-A1 | High viscosity liquid controlled delivery system and medical or surgical device | MMP1, MMP13, MMP9 | GPR84 2110/4885FFAR1 4101/4885FFAR4 4370/4885 |
| US-20130345260-A1 | High Viscosity Liquid Controlled Delivery System and Medical or Surgical Device | MMP1, MMP13, MMP9 | GPR84 2124/4885FFAR1 4158/4885FFAR4 4407/4885 |
| US-20080145419-A1 | High viscosity liquid controlled delivery system and medical or surgical device | MMP1, MMP13, MMP9 | GPR84 2110/4885FFAR1 4101/4885FFAR4 4370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.