Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7020973 | 0.95 | VCAM1 (0.58) | VCAM1CYP19A1LMNATSHRCYP3A4 | |
| SCHEMBL27796862 | 0.85 | VCAM1 (0.48) | VCAM1CYP19A1TSHRCYP3A4SMN1; SMN2 | |
| SCHEMBL212845 | 0.81 | CYP19A1 (0.81) | VCAM1CYP19A1LMNATSHRCYP3A4 | |
| SCHEMBL25367923 | 0.80 | LMNA (0.46) | VCAM1CYP19A1LMNATSHRSMN1; SMN2 | |
| SCHEMBL4955596 | 0.80 | VCAM1 (0.44) | VCAM1CYP19A1LMNATSHRCYP3A4 | |
| SCHEMBL5497151 | 0.80 | ALDH1A1 (0.44) | VCAM1CYP19A1TSHRCYP3A4ALDH1A1 | |
| SCHEMBL1005421 | 0.78 | VCAM1 (1.00) | VCAM1CYP19A1LMNATSHRCYP3A4 | |
| SCHEMBL5494054 | 0.78 | VCAM1 (0.61) | VCAM1CYP19A1LMNATSHRCYP3A4 | |
| SCHEMBL9789477 | 0.78 | CYP19A1 (0.77) | VCAM1CYP19A1LMNATSHRCYP3A4 | |
| SCHEMBL16541066 | 0.78 | CYP19A1 (0.77) | VCAM1CYP19A1LMNATSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 344 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024101298-A1 | METHOD FOR PRODUCING MACROLIDE COMPOUND | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 2024-05-16 | — | — | WO | claimed |
| EP-3737947-B1 | METHODS FOR MEASURING ANALYTE AND/OR PROTEIN IN BIOLOGICAL SAMPLES | IDEXX LAB INC (US) | 2024-04-17 | — | — | EP | claimed |
| CN-111848710-A | Preparation method of nicotinamide ribose and reduction state and salt thereof | 深圳市迪克曼科技开发有限公司 | 2020-10-30 | — | — | CN | claimed |
| CN-103922986-B | Vildagliptin, vildagliptin analogues and vildagliptin intermediate, and preparation methods of three and application | 上海彩迩文生化科技有限公司 | 2017-02-15 | — | — | CN | claimed |
| CN-104098646-B | Gracillin derivative and antitumor activity application thereof | 云南省药物研究所 | 2017-01-11 | — | — | CN | claimed |
| CN-101970100-B | Novel chiral selectors and stationary phases for separating enantiomer mixtures | EVONIK DEGUSSA GMBH | 2015-06-03 | — | — | CN | claimed |
| CN-103922986-A | Vildagliptin, vildagliptin analogues and vildagliptin intermediate, and preparation methods of three and application | SHANGHAI CAIERWEN BIOCHEMICAL TECHNOLOGY CO LTD | 2014-07-16 | — | — | CN | claimed |
| EP-2252393-B1 | NOVEL CHIRAL SELECTORS AND STATIONARY PHASES FOR SEPARATING ENANTIOMER MIXTURES | EVONIK DEGUSSA GMBH (DE) | 2014-04-30 | — | — | EP | claimed |
| US-8647882-B2 | Chiral selectors and stationary phases for separating enantiomer mixtures | EVONIK DEGUSSA GMBH (DE) | 2014-02-11 | — | — | US | claimed |
| US-20120015443-A1 | NOVEL CHIRAL SELECTORS AND STATIONARY PHASES FOR SEPARATING ENANTIOMER MIXTURES | EVONIK DEGUSSA GMBH (DE) | 2012-01-19 | — | — | US | claimed |
| CN-1075635-A | immunosuppressant | ISHIHARA SANGYO KAISHA (JP) | 1993-09-01 | — | — | CN | claimed |
| EP-0181831-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE ACYLOXYAZETIDINONES | CIBA-GEIGY AG (CH) | 1993-08-25 | — | — | EP | claimed |
| EP-0553358-A1 | PROCESS FOR PRODUCING 3-DPA-LACTONE | Japan Tobacco Inc. (JP) | 1993-08-04 | — | — | EP | claimed |
| US-5202447-A | Stereospecific | TORAY INDUSTRIES, INC. (JP) | 1993-04-13 | — | — | US | claimed |
| EP-0206283-B1 | OPTICALLY ACTIVE PYRIDOBENZOXAZINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-01-27 | — | — | EP | claimed |
| EP-0463162-A1 | PREPARATION OF 5,6,7-TRINOR-4,8-INTER-m-PHENYLENE PGI 2 DERIVATIVES | TORAY INDUSTRIES, INC. (JP) | 1992-01-02 | — | — | EP | claimed |
| EP-0181831-A2 | Process for the preparation of optically active acyloxyazetidinones | CIBA-GEIGY AG (CH) | 1986-05-21 | — | — | EP | claimed |
| EP-0008599-B1 | SURFACTANT AND PHENOLIC FOAM PRODUCED THEREWITH | Celotex Corporation (US) | 1983-12-14 | — | — | EP | claimed |
| EP-0075629-A1 | Imidazole derivatives, their preparation, and their pharmaceutical compositions | Sumitomo Chemical Industries Ltd. (JP) | 1983-04-06 | — | — | EP | claimed |
| US-4097495-A | Tetramethyl-benzyloxy chromans | HOFFMANN-LA ROCHE INC. (US) | 1978-06-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015443-A1 | NOVEL CHIRAL SELECTORS AND STATIONARY PHASES FOR SEPARATING ENANTIOMER MIXTURES | BCAT2, BCAT1, SLC43A1 | VCAM1 2440/4885CYP19A1 1193/4885LMNA 2351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.