SCHEMBL3484650

SCHEMBL3484650

COc1ccc(Sc2ccc(C)cc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.71
RELA Q04206 1/20 0.56
PTGIR P43119 3/20 0.55
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
ALDH1A1 P00352 4/20 0.51
MAPT P10636 2/20 0.51
HPGD P15428 2/20 0.51
KDM4E B2RXH2 1/20 0.48
HTT P42858 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
NPC1 O15118 2/20 0.47
TP53 P04637 1/20 0.47
HAO1 Q9UJM8 1/20 0.47
RAB9A P51151 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12276817 0.94 ACHE (0.62) ACHERELAPTGIRCA12CA1
SCHEMBL14407926 0.94 ACHE (0.62) ACHERELAPTGIRCA12CA1
SCHEMBL482369 0.90 CA1 (0.65) ACHEPTGIRCA12CA1CA2
SCHEMBL12386987 0.88 ACHE (0.56) ACHERELAPTGIRCA12CA1
SCHEMBL8944197 0.88 ACHE (0.56) ACHERELAPTGIRCA12CA1
SCHEMBL18879551 0.88 ACHE (0.56) ACHERELAPTGIRALDH1A1MAPT
SCHEMBL12770845 0.88 ACHE (0.56) ACHERELAPTGIRALDH1A1MAPT
Hydrochloric Acid SCHEMBL11848856 0.87 CA1 (0.61) ACHEPTGIRCA12CA1CA2
SCHEMBL12708273 0.86 ACHE (0.71) ACHERELACA12CA1CA2
SCHEMBL12757104 0.85 MAPT (0.56) ACHEPTGIRCA1CA2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250339565-A1 METHOD FOR SYNTHESIZING IODO- OR ASTATOARYL COMPOUNDS USING ARYLSULFONIUM SALTS INST NAT SANTE RECH MED (FR) 2025-11-06 US disclosed
WO-2023222909-A1 METHOD FOR SYNTHESIZING IODO- OR ASTATOARYL COMPOUNDS USING ARYLSULFONIUM SALTS Institut National de la Santé et de la Recherche Médicale (FR) 2023-11-23 WO disclosed
WO-2023222909-A1 METHOD FOR SYNTHESIZING IODO- OR ASTATOARYL COMPOUNDS USING ARYLSULFONIUM SALTS Institut National de la Santé et de la Recherche Médicale (FR) 2023-11-23 WO disclosed
CN-107298650-B Heterocyclic carboxylic acid amide ligands and their use in copper catalyzed aryl halide coupling reactions 浙江中科创越药业有限公司 2022-11-15 CN disclosed
US-11427536-B2 Photocatalyst-free, light-induced carbon-sulfur cross-coupling methods THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2022-08-30 US disclosed
EP-3057688-B1 IMPROVING THE CHEMICAL STABILITY OF FILTRATION MEMBRANES BASF SE (DE) 2022-01-05 EP disclosed
WO-2021065767-A1 LAMP MEMBER RESIN COMPOSITION, LAMP MEMBER, AND METHOD FOR PRODUCING LAMP MEMBER RESIN COMPOSITION 住友化学株式会社 2021-04-08 WO disclosed
WO-2021065770-A1 AROMATIC POLYSULFONE COMPOSITION, MOLDED OBJECT, AND METHOD FOR PRODUCING AROMATIC POLYSULFONE COMPOSITION 住友化学株式会社 2021-04-08 WO disclosed
EP-2377599-B1 POROUS HOLLOW FIBER MEMBRANE TOYO BOSEKI (JP) 2020-09-02 EP disclosed
US-10759765-B2 Heterocyclic carboxylic acid amide ligand and applications thereof in copper catalyzed coupling reaction of aryl halogeno substitute CE PHARM CO., LTD. (CN) 2020-09-01 US disclosed
WO-2008012470-A2 SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES GENFIT (FR) 2008-01-31 WO disclosed
WO-2008012470-A2 SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES GENFIT (FR) 2008-01-31 WO disclosed
US-20070244120-A1 INHIBITION OF RAF KINASE USING SUBSTITUTED HETEROCYCLIC UREAS BAYER HEALTHCARE LLC 2007-10-18 US disclosed
US-20070244120-A1 INHIBITION OF RAF KINASE USING SUBSTITUTED HETEROCYCLIC UREAS BAYER HEALTHCARE LLC 2007-10-18 US disclosed
US-20070196721-A1 Crosslinkable sulfonated copolymer and fuel cell including polymeric composition of the same SAMSUNG SDI CO., LTD. (KR) 2007-08-23 US disclosed
EP-1806337-A1 METHOD FOR PRODUCING THIOETHER COMPOUND BANYU PHARMACEUTICAL CO., LTD. (JP) 2007-07-11 EP disclosed
WO-2007064869-A2 CATALYSTS FOR ARYL SULFIDE SYNTHESIS AND METHOD OF PRODUCING ARYL SULFIDES YALE UNIVERSITY (US) 2007-06-07 WO disclosed
WO-2007064869-A2 CATALYSTS FOR ARYL SULFIDE SYNTHESIS AND METHOD OF PRODUCING ARYL SULFIDES YALE UNIVERSITY (US) 2007-06-07 WO disclosed
CN-1916760-A Acid generator, sulfonic acid derivative and radiation-sensitive resin composition JSR CORP (JP) 2007-02-21 CN disclosed
CN-1276303-C Acid generator and radiation-sensitive resin composition JSR CORP (JP) 2006-09-20 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070244120-A1 INHIBITION OF RAF KINASE USING SUBSTITUTED HETEROCYCLIC UREAS BRAF, RAF1, ARAF ACHE 4822/4885RELA 1899/4885PTGIR 3208/4885
US-20250339565-A1 METHOD FOR SYNTHESIZING IODO- OR ASTATOARYL COMPOUNDS USING ARYLSULFONIUM SALTS ARSA, STS, AADAC ACHE 235/4885RELA 4646/4885PTGIR 3132/4885
US-10759765-B2 Heterocyclic carboxylic acid amide ligand and applications thereof in copper catalyzed coupling reaction of aryl halogeno substitute AOC1, AOC2, AOC3 ACHE 2315/4885RELA 3068/4885PTGIR 3152/4885
US-11427536-B2 Photocatalyst-free, light-induced carbon-sulfur cross-coupling methods TST, CBS, CRY2 ACHE 2054/4885RELA 306/4885PTGIR 4107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.