Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 10/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25280689 | 0.79 | AR (0.37) | CYP1A2CYP2C9CYP2C19HPGDCASP1 | |
| SCHEMBL31476409 | 0.71 | PGR (0.41) | CYP1A2CYP2C9CYP2C19ALDH1A1KDM4E | |
| SCHEMBL21750720 | 0.71 | PAX8 (0.44) | CYP1A2CYP2C9CYP2C19HPGDCASP1 | |
| SCHEMBL3379896 | 0.66 | KMT2A (0.54) | CYP1A2CYP2C9CYP2C19HPGDCASP1 | |
| SCHEMBL17262945 | 0.64 | NPSR1 (0.41) | CYP1A2CYP2C9CYP2C19HPGDCASP1 | |
| SCHEMBL15031983 | 0.64 | CYP3A4 (0.53) | CYP2C9MYCNR4A1ALDH1A1GSTA1 | |
| SCHEMBL21812547 | 0.63 | GSTA1 (0.77) | CYP1A2CYP2C9CYP2C19HPGDALOX15 | |
| SCHEMBL3485083 | 0.63 | ALDH1A1 (0.41) | CYP1A2CYP2C9CYP2C19CASP1ALDH1A1 | |
| SCHEMBL467470 | 0.63 | ALDH1A1 (0.61) | CYP1A2CYP2C9CYP2C19HPGDALOX15 | |
| SCHEMBL618056 | 0.63 | KDM4E (0.65) | CYP1A2CYP2C9CYP2C19HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163910-B2 | Amide-substituted xanthene dyes | ELITECH HOLDING B.V. (NL) | 2012-04-24 | — | — | US | disclosed |
| US-20090093612-A1 | AMIDE-SUBSTITUTED XANTHENE DYES | EPOCH BIOSCIENCES, INC. (US) | 2009-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093612-A1 | AMIDE-SUBSTITUTED XANTHENE DYES | ANXA5, PHOSPHO1, TPST2 | CYP1A2 3725/4885CYP2C9 4083/4885CYP2C19 4420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.