Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3485146 | 0.80 | CTSA (0.38) | MAPTKDM4EALDH1A1ALOX15MAPK1 | |
| SCHEMBL13748939 | 0.78 | CA1 (0.44) | CYP3A4MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL10905476 | 0.72 | RAB9A (0.47) | ADRA2AADRA1ACYP3A4ALDH1A1LMNA | |
| SCHEMBL1520565 | 0.70 | ADRA1A (0.54) | ADRA2AADRA1AAOC3MAPTALDH1A1 | |
| SCHEMBL5469559 | 0.69 | MAPK1 (0.52) | CYP3A4MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL9335491 | 0.69 | MAPK1 (0.46) | CYP3A4MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL12957854 | 0.67 | MAPT (0.45) | CYP3A4MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL15105506 | 0.67 | ACHE (0.43) | CYP3A4MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL6571131 | 0.66 | IDO1 (0.44) | CYP3A4MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL16704713 | 0.66 | MAPT (0.43) | CYP3A4MAPTKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100028952-A1 | FERMENTATION AND PURIFICATION OF ACTINOMADURA CHROMOPROTEIN AND RELATED SPECIES | WYETH (US) | 2010-02-04 | — | — | US | disclosed |
| EP-2029175-A2 | FERMENTATION AND PURIFICATION OF ACTINOMADURA CHROMOPROTEIN AND RELATED SPECIES | Wyeth (US) | 2009-03-04 | — | — | EP | disclosed |
| US-20080274959-A1 | Actinomadura Chromoprotein, Apoprotein and Gene Cluster | WYETH (US) | 2008-11-06 | — | — | US | disclosed |
| WO-2007149560-A9 | FERMENTATION AND PURIFICATION OF ACTINOMADURA CHROMOPROTEIN AND RELATED SPECIES | WYETH CORP (US) | 2008-07-24 | — | — | WO | disclosed |
| WO-2007149560-A2 | FERMENTATION AND PURIFICATION OF ACTINOMADURA CHROMOPROTEIN AND RELATED SPECIES | WYETH (US) | 2007-12-27 | — | — | WO | disclosed |
| EP-1836219-A2 | ACTINOMADURA CHROMOPROTEIN, APOPROTEIN, AND GENE CLUSTER | Wyeth (US) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006066153-A2 | ACTINOMADURA CHROMOPROTEIN, APOPROTEIN, AND GENE CLUSTER | WYETH (US) | 2006-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080274959-A1 | Actinomadura Chromoprotein, Apoprotein and Gene Cluster | ACTR2, APOB, CACYBP | ADRA2A 639/4885ADRA1A 1294/4885AOC3 1077/4885 |
| US-20100028952-A1 | FERMENTATION AND PURIFICATION OF ACTINOMADURA CHROMOPROTEIN AND RELATED SPECIES | DCXR, ACTR2, AMY2A | ADRA2A 901/4885ADRA1A 1681/4885AOC3 1936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.