Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3488086 | 0.87 | MMP1 (0.49) | SIGMAR1MMP1MMP13KDM4EALDH1A1 | |
| SCHEMBL13434255 | 0.86 | L3MBTL1 (0.45) | SIGMAR1MMP1MMP13EPHX2ALDH1A1 | |
| SCHEMBL2242813 | 0.79 | SIGMAR1 (0.48) | SIGMAR1EPHX2ALDH1A1LMNAHRH3 | |
| SCHEMBL13434254 | 0.73 | CYP3A4 (0.47) | MMP1MMP13ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL3488949 | 0.72 | KMT2A (0.45) | SIGMAR1MMP1MMP13EPHX2ALDH1A1 | |
| SCHEMBL3488955 | 0.72 | KMT2A (0.45) | SIGMAR1MMP1MMP13EPHX2ALDH1A1 | |
| SCHEMBL22946306 | 0.71 | GAA (0.59) | SIGMAR1KDM4EALDH1A1LMNAL3MBTL1 | |
| SCHEMBL19876042 | 0.71 | SIGMAR1 (0.50) | SIGMAR1KDM4EMCHR1HRH3MEN1 | |
| SCHEMBL19875945 | 0.71 | SIGMAR1 (0.50) | SIGMAR1KDM4EMCHR1HRH3MEN1 | |
| SCHEMBL19875824 | 0.71 | SIGMAR1 (0.52) | SIGMAR1MMP1MMP13EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056497-A1 | AMIDE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056497-A1 | AMIDE DERIVATIVE | REN, AGTR1, AGTR2 | SIGMAR1 570/4885MMP1 610/4885MMP13 1349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.