Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3489489 | 0.91 | GAA (0.48) | GAACA1CA2ALDH1A1LMNA | |
| SCHEMBL3488972 | 0.79 | ALDH1A1 (0.53) | CA1CA2ALDH1A1LMNAALB | |
| SCHEMBL18221849 | 0.78 | ALDH1A1 (0.60) | RAB9AGAACA2ALDH1A1LMNA | |
| SCHEMBL27538377 | 0.77 | ALDH1A1 (0.54) | RAB9AALDH1A1LMNAALBCYP2C9 | |
| SCHEMBL1395612 | 0.75 | ALDH1A1 (0.72) | RAB9AGAAALDH1A1LMNANPSR1 | |
| SCHEMBL11058142 | 0.75 | ALDH1A1 (0.55) | CA1CA2ALDH1A1LMNAALB | |
| SCHEMBL7756413 | 0.74 | MMP2 (0.53) | RAB9AGAACA1CA2ALDH1A1 | |
| SCHEMBL13435328 | 0.74 | GAA (0.50) | RAB9AGAAALDH1A1LMNAALB | |
| SCHEMBL29025356 | 0.74 | EPHX2 (0.57) | RAB9ALMNATSHRTDP1L3MBTL1 | |
| SCHEMBL25206305 | 0.74 | ALDH1A1 (0.48) | GAACA1CA2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150359899-A1 | MEANS AND METHODS OF ENHANCING DELIVERY TO BIOLOGICAL SYSTEMS | BOTTI PAOLO (CH) | 2015-12-17 | — | — | US | disclosed |
| US-9211340-B2 | Means and methods of enhancing delivery to biological systems | CAPSUGEL BELGIUM (BE) | 2015-12-15 | — | — | US | disclosed |
| EP-2561891-A2 | Means and methods of enhancing delivery to biological systems | Botti, Paolo (CH) | 2013-02-27 | — | — | EP | disclosed |
| US-20100062050-A1 | MEANS AND METHODS OF ENHANCING DELIVERY TO BIOLOGICAL SYSTEMS | CAPSUGEL BELGIUM (BE) | 2010-03-11 | — | — | US | disclosed |
| EP-2068936-A2 | MEANS AND METHODS OF ENHANCING DELIVERY TO BIOLOGICAL SYSTEMS | Botti, Paolo (CH) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008037463-A2 | MEANS AND METHODS OF ENHANCING DELIVERY TO BIOLOGICAL SYSTEMS | BOTTI PAOLO (CH) | 2008-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100062050-A1 | MEANS AND METHODS OF ENHANCING DELIVERY TO BIOLOGICAL SYSTEMS | SGTA, GHRHR, IL36G | RAB9A 3683/4885GAA 673/4885CA1 1547/4885 |
| US-20150359899-A1 | MEANS AND METHODS OF ENHANCING DELIVERY TO BIOLOGICAL SYSTEMS | PTMS, HGFAC, SLC43A1 | RAB9A 3508/4885GAA 474/4885CA1 1177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.