Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALB | P02768 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | FBP1 | P09467 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3489662 | 0.88 | ALDH1A1 (0.51) | ALDH1A1LMNAALBCYP2C9TSHR | |
| SCHEMBL11058142 | 0.84 | ALDH1A1 (0.55) | ALDH1A1LMNAALBCYP2C9TSHR | |
| SCHEMBL27538377 | 0.84 | ALDH1A1 (0.54) | ALDH1A1LMNAALBCYP2C9TSHR | |
| SCHEMBL30490037 | 0.79 | CA12 (0.67) | ALDH1A1LMNAHTTNPSR1CA2 | |
| SCHEMBL3490607 | 0.79 | RAB9A (0.46) | ALDH1A1LMNAALBCYP2C9TSHR | |
| SCHEMBL9316028 | 0.78 | MMP2 (0.61) | ALDH1A1LMNACYP2C9TDP1NPSR1 | |
| SCHEMBL4095386 | 0.78 | ALDH1A1 (0.48) | ALDH1A1LMNAALBCYP2C9TSHR | |
| SCHEMBL4433373 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNAALBCYP2C9TSHR | |
| SCHEMBL29438757 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNAALBCYP2C9TSHR | |
| SCHEMBL27513081 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNAALBCYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150359899-A1 | MEANS AND METHODS OF ENHANCING DELIVERY TO BIOLOGICAL SYSTEMS | BOTTI PAOLO (CH) | 2015-12-17 | — | — | US | disclosed |
| US-9211340-B2 | Means and methods of enhancing delivery to biological systems | CAPSUGEL BELGIUM (BE) | 2015-12-15 | — | — | US | disclosed |
| EP-2561891-A2 | Means and methods of enhancing delivery to biological systems | Botti, Paolo (CH) | 2013-02-27 | — | — | EP | disclosed |
| US-20100062050-A1 | MEANS AND METHODS OF ENHANCING DELIVERY TO BIOLOGICAL SYSTEMS | CAPSUGEL BELGIUM (BE) | 2010-03-11 | — | — | US | disclosed |
| CN-101557829-A | Apparatus and method for enhancing delivery to biological systems | PAOLO BOTTI (CH) | 2009-10-14 | — | — | CN | disclosed |
| EP-2068936-A2 | MEANS AND METHODS OF ENHANCING DELIVERY TO BIOLOGICAL SYSTEMS | Botti, Paolo (CH) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008037463-A2 | MEANS AND METHODS OF ENHANCING DELIVERY TO BIOLOGICAL SYSTEMS | BOTTI PAOLO (CH) | 2008-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100062050-A1 | MEANS AND METHODS OF ENHANCING DELIVERY TO BIOLOGICAL SYSTEMS | SGTA, GHRHR, IL36G | ALDH1A1 1259/4885LMNA 3031/4885ALB 113/4885 |
| US-20150359899-A1 | MEANS AND METHODS OF ENHANCING DELIVERY TO BIOLOGICAL SYSTEMS | PTMS, HGFAC, SLC43A1 | ALDH1A1 1096/4885LMNA 1616/4885ALB 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.