Carpipramine

Carpipramine

SCHEMBL34949

NC(=O)C1(N2CCCCC2)CCN(CCCN2c3ccccc3CCc3ccccc32)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 8/20 1.00
CHRM2 P08172 6/20 1.00
CHRM1 P11229 6/20 1.00
ADRA1A P35348 3/20 1.00
HTR1A P08908 2/20 1.00
ADRA2A P08913 2/20 1.00
DRD1 P21728 2/20 1.00
SLC6A4 P31645 2/20 1.00
OPRM1 P35372 2/20 1.00
SLC6A3 Q01959 2/20 1.00
KCNH2 Q12809 2/20 1.00
HRH3 Q9Y5N1 2/20 1.00
TBXA2R P21731 1/20 1.00
SLC6A2 P23975 1/20 1.00
TSHR P16473 1/20 0.56
ALDH1A1 P00352 3/20 0.48
TP53 P04637 1/20 0.48
DRD4 P21917 7/20 0.47
DRD2 P14416 6/20 0.46
CHRM4 P08173 5/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carpipramine SCHEMBL29913255 1.00 DRD3 (1.00) DRD3CHRM2CHRM1ADRA1AHTR1A
Carpipramine SCHEMBL27478838 1.00 DRD3 (1.00) DRD3CHRM2CHRM1ADRA1AHTR1A
Carpipramine SCHEMBL969084 0.99 DRD3 (0.98) DRD3CHRM2CHRM1ADRA1AHTR1A
Carpipramine SCHEMBL7353292 0.99 DRD3 (0.98) DRD3CHRM2CHRM1ADRA1AHTR1A
Carpipramine SCHEMBL365672 0.99 DRD3 (0.98) DRD3CHRM2CHRM1ADRA1AHTR1A
Carpipramine SCHEMBL969082 0.98 DRD3 (0.96) DRD3CHRM2CHRM1ADRA1AHTR1A
Carpipramine SCHEMBL29356300 0.98 DRD3 (0.96) DRD3CHRM2CHRM1ADRA1AHTR1A
Carpipramine SCHEMBL17747956 0.98 DRD3 (0.96) DRD3CHRM2CHRM1ADRA1AHTR1A
Carpipramine SCHEMBL17747957 0.98 DRD3 (0.96) DRD3CHRM2CHRM1ADRA1AHTR1A
Carpipramine SCHEMBL1648924 0.97 DRD3 (0.94) DRD3CHRM2CHRM1ADRA1AHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1640 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4674482-A2 PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR BEHAVIORAL AND PSYCHOLOGICAL SYMPTOMS ASSOCIATED WITH NEURODEGENERATIVE DISEASE OR IMPULSIVE SYMPTOMS ASSOCIATED WITH MENTAL DISEASE CONTAINING BREXPIPRAZOLE OR SALT THEREOF Otsuka Pharmaceutical Co., Ltd. (JP) 2026-01-07 EP claimed
US-20250295611-A1 METHODS OF TREATING 5HT2A RECEPTOR-MEDIATED CONDITIONS TESSELLATE THERAPEUTICS INC (US) 2025-09-25 US claimed
EP-4618973-A1 METHODS OF SWITCHING NEUROPSYCHIATRIC MEDICATIONS USING ULOTARONT Sumitomo Pharma America, Inc. (US) 2025-09-24 EP claimed
US-12310974-B1 Method of treating post-traumatic stress disorder with carpipramine AVICENNE INVEST, S.A. (LU) 2025-05-27 US claimed
US-20250099459-A1 PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR BEHAVIORAL AND PSYCHOLOGICAL SYMPTOMS ASSOCIATED WITH NEURODEGENERATIVE DISEASE OR IMPULSIVE SYMPTOMS ASSOCIATED WITH MENTAL DISEASE CONTAINING BREXPIPRAZOLE OR SALT THEREOF OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2025-03-27 US claimed
WO-2024107681-A1 METHODS OF SWITCHING NEUROPSYCHIATRIC MEDICATIONS USING ULOTARONT SUMITOMO PHARMA AMERICA, INC. (US) 2024-05-23 WO claimed
WO-2023212244-A1 METHODS OF TREATING 5HT2A RECEPTOR-MEDIATED CONDITIONS TESSELLATE THERAPEUTICS, INC. (US) 2023-11-02 WO claimed
US-20230321073-A1 COMPOSITIONS AND METHODS FOR TREATING METABOLIC DYSREGULATION Response IP Holding Company, LLC (US) 2023-10-12 US claimed
US-20230218623-A1 SALTS OF NEUROCEUTICALS AND USES THEREOF SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2023-07-13 US claimed
EP-4192579-A2 COMPOSITIONS AND METHODS FOR TREATING METABOLIC DYSREGULATION Response IP Holding Company, LLC (US) 2023-06-14 EP claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
EP-0669128-B1 SUSTAINED-RELEASE MICROSPHERE CONTAINING ANTIPSYCHOTIC AND PROCESS FOR PRODUCING THE SAME YOSHITOMI PHARMACEUTICAL (JP) 2000-01-05 EP claimed
US-5871778-A Sustained release microsphere preparation containing antipsychotic drug YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1999-02-16 US claimed
US-5811547-A Method for inducing crystalline state transition in medicinal substance NIPPON SHINYAJU CO., LTD. (JP) 1998-09-22 US claimed
WO-1996001631-A1 NOVEL COMBINATION PRODUCT COMPRISING CAPRIPRAMINE AND A NEUROLEPTIC PIERRE FABRE MEDICAMENT (FR) 1996-01-25 WO claimed
EP-0669128-A1 SUSTAINED-RELEASE MICROSPHERE CONTAINING ANTIPSYCHOTIC AND PROCESS FOR PRODUCING THE SAME YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1995-08-30 EP claimed
US-4956362-A Use of carpipramine for the treatment of anxiety and sleep disorders Rhone-Poulenc Sante, a French Body Corporate (FR) 1990-09-11 US claimed
EP-0374042-A2 Use of carbipramine in the preparation of a medicament for the treatment of anxiety and sleeping disorders RHONE-POULENC SANTE (FR) 1990-06-20 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12310974-B1 Method of treating post-traumatic stress disorder with carpipramine SLC6A2, FKBP4, CRH DRD3 258/4885CHRM2 3483/4885CHRM1 4121/4885
US-20250295611-A1 METHODS OF TREATING 5HT2A RECEPTOR-MEDIATED CONDITIONS HTR2A, HTR5A, HTR6 DRD3 829/4885CHRM2 123/4885CHRM1 269/4885
US-20230321073-A1 COMPOSITIONS AND METHODS FOR TREATING METABOLIC DYSREGULATION LIPC, CPT1A, CETP DRD3 4793/4885CHRM2 4037/4885CHRM1 4551/4885
US-20250099459-A1 PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR BEHAVIORAL AND PSYCHOLOGICAL SYMPTOMS ASSOCIATED WITH NEURODEGENERATIVE DISEASE OR IMPULSIVE SYMPTOMS ASSOCIATED WITH MENTAL DISEASE CONTAINING BREXPIPRAZOLE OR SALT THEREOF SLC6A3, SLC6A2, SNCA DRD3 208/4885CHRM2 2864/4885CHRM1 2273/4885
US-20230218623-A1 SALTS OF NEUROCEUTICALS AND USES THEREOF SLC1A2, GABRA6, GABRA2 DRD3 2212/4885CHRM2 663/4885CHRM1 879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.