Adenosine Triphosphate

Adenosine Triphosphate

SCHEMBL3498798

Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O.O.[NaH].[NaH]

nearest known ligand 0.91

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Adenosine Triphosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 known ✓ P07550 1/20 0.80
ADORA1 known ✓ P30542 1/20 0.80
PDE4D known ✓ Q08499 1/20 0.80
PDE3A known ✓ Q14432 1/20 0.80
P2RY1 P47900 7/20 0.91
P2RX1 P51575 4/20 0.91
P2RX3 P56373 4/20 0.91
P2RY2 P41231 3/20 0.91
P2RX2 Q9UBL9 2/20 0.91
SRC P12931 2/20 0.91
SMN1; SMN2 Q16637 2/20 0.91
ALDH1A1 P00352 2/20 0.91
P2RX4 Q99571 1/20 0.91
RNASEL Q05823 4/20 0.88
TRPM2 O94759 2/20 0.84
MACROD2 A1Z1Q3 1/20 0.84
SIRT6 Q8N6T7 1/20 0.84
MACROD1 Q9BQ69 1/20 0.84
DNPH1 O43598 1/20 0.80
PRKAB2 O43741 1/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adenosine Triphosphate SCHEMBL4594616 1.00 P2RY1 (0.91) P2RY1P2RX1P2RX3P2RY2P2RX2
Adenosine Triphosphate SCHEMBL1496267 0.99 P2RY1 (0.93) P2RY1P2RX1P2RX3P2RY2P2RX2
Adenosine Triphosphate SCHEMBL28358 0.99 P2RY1 (0.93) P2RY1P2RX1P2RX3P2RY2P2RX2
Adenosine Triphosphate SCHEMBL3459127 0.99 P2RY1 (0.93) P2RY1P2RX1P2RX3P2RY2P2RX2
Adenosine Triphosphate SCHEMBL193647 0.99 P2RY1 (0.93) P2RY1P2RX1P2RX3P2RY2P2RX2
Adenosine Triphosphate SCHEMBL193645 0.99 P2RY1 (0.93) P2RY1P2RX1P2RX3P2RY2P2RX2
Adenosine Triphosphate SCHEMBL7133726 0.99 P2RY1 (0.93) P2RY1P2RX1P2RX3P2RY2P2RX2
Adenosine Triphosphate SCHEMBL28356 0.99 P2RY1 (0.93) P2RY1P2RX1P2RX3P2RY2P2RX2
Adenosine Diphosphate SCHEMBL11579612 0.99 P2RY1 (0.89) P2RY1P2RX1P2RX3P2RY2P2RX2
Adenosine Triphosphate SCHEMBL19834218 0.99 P2RY1 (0.93) P2RY1P2RX1P2RX3P2RY2P2RX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12533376-B2 Prophylactic or therapeutic agent for disease induced by oxidative stress OSAKA UNIVERSITY (JP) 2026-01-27 US disclosed
CN-119318713-A Application of TRPC3 inhibitor in preparation of cervical cancer treatment drugs and TRPC3 in preparation of cervical cancer diagnosis products 广西医科大学第一附属医院 2025-01-17 CN disclosed
CN-118929595-A Preparation method of stable magnesium-doped amorphous calcium phosphate nano-particles 昆明理工大学 2024-11-12 CN disclosed
US-11634545-B2 Layered-substance-containing solution and method of manufacturing same ADEKA CORPORATION (JP) 2023-04-25 US disclosed
CN-115835871-A Amorphous calcium carbonate for treating acidosis 阿莫菲克公司 2023-03-21 CN disclosed
CN-109071454-B Sulfonylureas and related compounds and uses thereof 昆士兰大学 2023-02-17 CN disclosed
CN-110088209-B Layered substance-containing liquid and method for producing same 株式会社ADEKA 2023-01-31 CN disclosed
CN-114948992-A Amorphous calcium carbonate for the treatment of leukemia 艾玛菲克有限公司 2022-08-30 CN disclosed
US-20210205172-A1 DRUG MANAGEMENT METHOD FOR KIT FORMULATION REQUIRING DOSE ADJUSTMENT REGIMEN KIT INC (JP) 2021-07-08 US disclosed
US-11045510-B2 Combination of aqueous extracts of watercress and nasturtium and ATP for use in the treatment of alopecia PIERRE FABRE DERMO-COSMETIQUE (FR) 2021-06-29 US disclosed
CN-103663532-A Method for preparing amorphous calcium carbonate nanospheres SHANGHAI INST CERAMICS 2014-03-26 CN disclosed
CN-102795610-B Amorphous calcium phosphate nanoball and preparation method thereof SHANGHAI INST CERAMICS 2014-01-22 CN disclosed
CN-102795610-A Amorphous calcium phosphate nanoball and preparation method thereof SHANGHAI INST CERAMICS 2012-11-28 CN disclosed
US-20100159449-A1 Continuous Assay Method for Measuring Receptor- and Ion Channel-Mediated Calcium Response and Subsequent Gene Expression NOACELL SCIENCE CO., LTD. (JP) 2010-06-24 US disclosed
US-7569558-B2 Topical delivery of trace metals for skin care BIODERM RESEARCH (US) 2009-08-04 US disclosed
EP-2036986-A1 CONTINUOUS ASSAY METHOD FOR MEASURING RECEPTOR- AND ION CHANNEL-MEDIATED CALCIUM RESPONSE AND SUBSEQUENT GENE EXPRESSION Noacell Science Co., Ltd. (JP) 2009-03-18 EP disclosed
US-20060183708-A1 Topical Delivery of Trace Metals for Enzyme Modulation BIODERM RESEARCH (US) 2006-08-17 US disclosed
WO-2006023710-A2 COSMETIC OR PHARMACEUTICAL COMPOSITION FOR SKIN CARE INFINITY2 HEALTH SCIENCES, INC. (US) 2006-03-02 WO disclosed
US-20060039887-A1 Cosmetic or pharmaceutical composition for skin care INFINITY2 HEALTH SCIENCES, INC. 2006-02-23 US disclosed
US-20040105894-A1 Trace Metals synergized copper nucleotides and copper glycosides for anti-aging and antiviral compositions GUPTA SHYAM K (US) 2004-06-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12533376-B2 Prophylactic or therapeutic agent for disease induced by oxidative stress LPO, SI, TNF ADRB2 3396/4885ADORA1 3867/4885PDE4D 3494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.