SCHEMBL351547

SCHEMBL351547

CC(C)(O)C(C)(C)OB(O)c1cccnc1

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
CYP1A2 P05177 2/20 0.33
CYP3A4 P08684 2/20 0.33
KIF11 P52732 1/20 0.33
LMNA P02545 1/20 0.33
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
THRB P10828 1/20 0.33
CYP19A1 P11511 5/20 0.33
NAPRT Q6XQN6 1/20 0.33
CYP17A1 P05093 2/20 0.32
KMT2A Q03164 2/20 0.32
CHRNB2 P17787 1/20 0.32
CHRNA4 P43681 1/20 0.32
CYP2A6 P11509 1/20 0.31
ALOX5 P09917 1/20 0.31
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL574865 0.80 CYP19A1 (0.32) KIF11CYP19A1
SCHEMBL1502646 0.80 CYP19A1 (0.31) CYP19A1
SCHEMBL119711 0.79 TRPV6 (0.39) ALDH1A1
SCHEMBL454794 0.79
SCHEMBL12615910 0.78 NPC1 (0.36) ALDH1A1CYP1A2CYP3A4KIF11CYP11B1
SCHEMBL20600817 0.78 CA4 (0.38) ALDH1A1CYP1A2CYP3A4KIF11LMNA
SCHEMBL532324 0.77 KMT2A (0.36) KMT2A
SCHEMBL1935838 0.77 PTGS2 (0.39) ALDH1A1CYP1A2CYP3A4KIF11CYP11B1
SCHEMBL2270306 0.75 ALDH1A1 (0.43) ALDH1A1CYP1A2CYP3A4LMNACYP11B1
SCHEMBL8131766 0.75 ALDH1A1 (0.41) ALDH1A1CYP1A2CYP3A4LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 343 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111004264-B Preparation method of N-substituted tetrahydropyridine-3/4-boric acid/ester 沧州普瑞东方科技有限公司 2022-05-17 CN claimed
CN-111349138-A Method for preparing abiraterone acetate 江苏恒瑞医药股份有限公司 2020-06-30 CN claimed
CN-111205269-A Preparation method and application preparation of carbazole-based organic electrophosphorescent material composition 上海百豪新材料有限公司 2020-05-29 CN claimed
CN-111004264-A Preparation method of N-substituted tetrahydropyridine-3/4-boric acid/ester 沧州普瑞东方科技有限公司 2020-04-14 CN claimed
CN-109705186-A A kind of preparation method of Abiraterone acetate 奥锐特药业股份有限公司 2019-05-03 CN claimed
CN-106532120-B A kind of nonaqueous electrolytic solution and the lithium secondary battery using the electrolyte 广州天赐高新材料股份有限公司 2019-02-01 CN claimed
US-9663550-B2 Method for preparing abiraterone acetate Wuhan Biocause Pharmaceutical Development Co., Ltd. (CN) 2017-05-30 US claimed
US-20160237109-A1 Method for Preparing Abiraterone Acetate Wuhan Biocause Pharmaceutical Development Co., Ltd. (CN) 2016-08-18 US claimed
CN-103951705-B A kind of take carbazole as the bipolarity small molecule host material with butterfly-like shape and the preparation method of core SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) 2016-04-13 CN claimed
US-12637442-B2 Organic electronic material containing nitrogen atom heterocyclic ring, preparation method therefor and application thereof Shanghai Chuanqin New Material Co., Ltd (CN) 2026-05-26 US disclosed
CN-122036730-A Gαq/11 protein inhibitor with purine skeleton, and preparation method and application thereof 中山大学 2026-05-15 CN disclosed
EP-4741392-A1 1H-PYRAZOLO[4,3-C]PYRIDINE COMPOUND, AND COMPOSITION THEREOF AND USE THEREOF Shenzhen TargetRx Co., Ltd. (CN) 2026-05-13 EP disclosed
EP-4695236-A1 SUBSTITUTED PHENYL-PIPERAZINYL BASED MODULATORS FOR THE TREATMENT OF DISEASE Soley Therapeutics, Inc. (US) 2026-02-18 EP disclosed
EP-4344702-B1 PYRAZOLYL DERIVATIVES USEFUL AS ANTI-CANCER AGENTS NOVARTIS AG (CH) 2026-01-28 EP disclosed
US-7361763-B2 Pyrrolo-pyridine kinase modulators SGX PHARMACEUTICALS, INC. (US) 2008-04-22 US disclosed
WO-2007106236-A2 PYRROLO-PYRIDINE KINASE MODULATORS SGX PHARMACEUTICALS, INC. (US) 2007-09-20 WO disclosed
EP-1781654-A1 PYRROLO-PYRIDINE KINASE MODULATORS SGX Pharmaceuticals, Inc. (US) 2007-05-09 EP disclosed
US-20070043068-A1 to treat diseases mediated by kinase activity; for example: [3-(2-methoxy-phenyl)-1H-pyrrolo[2,3-b]pyridine-5-yl]-methyl-phenyl-amine SGX PHARMACEUTICALS, INC. (US) 2007-02-22 US disclosed
US-20060030583-A1 Pyrrolo-pyridine kinase modulators SGX PHARMACEUTICALS, INC. (US) 2006-02-09 US disclosed
WO-2006015123-A1 PYRROLO-PYRIDINE KINASE MODULATORS SGX PHARMACEUTICALS, INC. (US) 2006-02-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637442-B2 Organic electronic material containing nitrogen atom heterocyclic ring, preparation method therefor and application thereof EML4, CTNNA1, TCF7L2 ALDH1A1 340/4885CYP1A2 761/4885CYP3A4 258/4885
US-20160237109-A1 Method for Preparing Abiraterone Acetate NR5A1, HSD17B7, CYP17A1 ALDH1A1 1029/4885CYP1A2 575/4885CYP3A4 530/4885
US-20060030583-A1 Pyrrolo-pyridine kinase modulators MAP3K20, MAP4K2, MAP3K19 ALDH1A1 4474/4885CYP1A2 4275/4885CYP3A4 3697/4885
US-20070043068-A1 to treat diseases mediated by kinase activity; for example: [3-(2-methoxy-phenyl)-1H-pyrrolo[2,3-b]pyridine-5-yl]-methyl-phenyl-amine MAP3K20, MAP4K2, MAP3K6 ALDH1A1 4281/4885CYP1A2 4330/4885CYP3A4 4563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.