Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 13/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL215272 | 0.80 | HDAC3 (0.50) | HDAC3HDAC1HDAC2NCOR2HDAC6 | |
| SCHEMBL6247309 | 0.78 | HDAC3 (0.53) | HDAC3HDAC1HDAC2NCOR2HDAC6 | |
| SCHEMBL8720375 | 0.78 | HDAC3 (0.53) | HDAC3HDAC1HDAC2NCOR2HDAC6 | |
| SCHEMBL21759520 | 0.78 | DUT (0.37) | HDAC3HDAC1HDAC2NCOR2HDAC6 | |
| SCHEMBL24327270 | 0.76 | HDAC3 (0.43) | HDAC3HDAC1HDAC2NCOR2HDAC6 | |
| SCHEMBL867417 | 0.76 | PRSS1 (0.47) | HDAC3HDAC1HDAC2NCOR2HDAC6 | |
| SCHEMBL29922455 | 0.75 | TLR8 (0.49) | HDAC3HDAC1HDAC2NCOR2HDAC6 | |
| SCHEMBL1170549 | 0.75 | TLR8 (0.49) | HDAC3HDAC1HDAC2NCOR2HDAC6 | |
| SCHEMBL9759440 | 0.74 | CHRM2 (0.39) | HDAC3HDAC1HDAC2NCOR2HDAC6 | |
| SCHEMBL8082845 | 0.74 | L3MBTL1 (0.48) | HDAC3HDAC1HDAC2NCOR2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4736882-A2 | TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE | Cullgen (Shanghai), Inc. (CN) | 2026-05-06 | — | — | EP | disclosed |