Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | AHR | P35869 | 2/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | EED | O75530 | 1/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.37 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.36 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.36 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.36 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.35 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3787577 | 0.82 | ITGB2 (0.50) | AHRKDM4ESMN1; SMN2LMNA | |
| SCHEMBL10590722 | 0.77 | ABCG2 (0.50) | ABCG2GSK3BPKMTSHREED | |
| SCHEMBL7594061 | 0.76 | ABCG2 (0.55) | ABCG2GSK3BPKMTSHREED | |
| SCHEMBL30521296 | 0.74 | ABCG2 (0.52) | ABCG2GSK3BPKMTSHRCA2 | |
| SCHEMBL1224045 | 0.74 | ABCG2 (0.52) | ABCG2GSK3BPKMTSHRCA2 | |
| SCHEMBL506350 | 0.74 | EED (0.46) | ABCG2P2RX7GSK3BMT-CO2PKM | |
| SCHEMBL8499147 | 0.73 | ABCG2 (0.50) | ABCG2GSK3BPKMTSHREED | |
| SCHEMBL17922618 | 0.73 | ABCG2 (0.50) | ABCG2GSK3BPKMTSHREED | |
| SCHEMBL263096 | 0.73 | ABCG2 (0.50) | ABCG2GSK3BPKMTSHREED | |
| SCHEMBL10589684 | 0.73 | ABCG2 (0.50) | ABCG2GSK3BPKMTSHREED |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3766883-A1 | IMIDAXOPYROLONE COMPOUND AND APPLICATION THEREOF | Luoxin Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2021-01-20 | — | — | EP | disclosed |
| WO-2019174576-A1 | IMIDAXOPYROLONE COMPOUND AND APPLICATION THEREOF | 罗欣药业(上海)有限公司 | 2019-09-19 | — | — | WO | disclosed |
| CN-105143206-B | Pyrimidine -2,4- diamine derivative for treating cancer | 托马斯·黑勒戴药物研究基金会 | 2019-01-15 | — | — | CN | disclosed |
| EP-2366704-B1 | Inhibitors of serine proteases | VERTEX PHARMA (US) | 2013-10-23 | — | — | EP | disclosed |
| US-8148380-B2 | Antibacterial amide and sulfonamide substituted heterocyclic urea compounds | CRESTONE, INC. (US) | 2012-04-03 | — | — | US | disclosed |
| US-20120015941-A1 | Antibacterial Amide and Sulfonamide Substituted Heterocyclic Urea Compounds | CRESTONE, INC. (US) | 2012-01-19 | — | — | US | disclosed |
| EP-2366704-A1 | Inhibitors of serine proteases | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-09-21 | — | — | EP | disclosed |
| EP-2364984-A1 | Inhibitors of serine proteases | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-09-14 | — | — | EP | disclosed |
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| WO-2008106058-A2 | INHIBITORS OF SERINE PROTEASES | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-09-04 | — | — | WO | disclosed |
| EP-1481730-B1 | Process for the production of phenolic compounds using zeolite beta of the proton-type, | UBE INDUSTRIES (JP) | 2008-01-23 | — | — | EP | disclosed |
| US-7285688-B2 | Proton type β zeolite, preparation method thereof and process for preparing phenol compound using the same | UBE INDUSTRIES, LTD. (JP) | 2007-10-23 | — | — | US | disclosed |
| WO-2007025307-A2 | INHIBITORS OF SERINE PROTEASES | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2007-03-01 | — | — | WO | disclosed |
| CN-1572368-A | Novel proton type beta zeolite, preparation method thereof and process for preparing phenol compound using the same | UBE INDUSTRIES (JP) | 2005-02-02 | — | — | CN | disclosed |
| US-20040242938-A1 | Novel proton type beta zeolite, preparation method thereof and process for preparing phenol compound using the same | UBE INDUSTRIES, LTD. (JP) | 2004-12-02 | — | — | US | disclosed |
| EP-1481730-A1 | New zeolite beta of the proton-type, process for its preparation and production of phenolic compounds using the same | Ube Industries, Ltd. (JP) | 2004-12-01 | — | — | EP | disclosed |
| US-5296601-A | Reaction of aromatic chloride with carbon monoxide and alcohol | NIHON NOHYAKU CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0282266-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID AMIDES OR ESTERS | NIHON NOHYAKU CO., LTD. (JP) | 1992-09-09 | — | — | EP | disclosed |
| US-5142057-A | Reacting an organic chloride with carbon monoxide and amine | NIHON NOHYAKU CO., LTD. (JP) | 1992-08-25 | — | — | US | disclosed |
| EP-0282266-A2 | Process for producing carboxylic acid amides or esters | NIHON NOHYAKU CO., LTD. (JP) | 1988-09-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242938-A1 | Novel proton type beta zeolite, preparation method thereof and process for preparing phenol compound using the same | HPD, PAH, TPSD1 | ABCG2 1195/4885AHR 186/4885P2RX7 1804/4885 |
| US-20120015941-A1 | Antibacterial Amide and Sulfonamide Substituted Heterocyclic Urea Compounds | NAAA, AADAC, RPSA | ABCG2 355/4885AHR 2036/4885P2RX7 2058/4885 |
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | ABCG2 31/4885AHR 83/4885P2RX7 656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.