Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306384 | 0.87 | GABRA1 (0.38) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL7994765 | 0.87 | APP (0.47) | CA12CA1CA2CA9CA14 | |
| SCHEMBL1306505 | 0.85 | APP (0.41) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL2854252 | 0.80 | CYP1A1 (0.44) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL19174201 | 0.78 | CYP1A1 (0.48) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL440124 | 0.78 | GRM5 (0.50) | CA12CA1CA2CA9GABRA1 | |
| SCHEMBL3347257 | 0.76 | GRM5 (0.48) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL1230907 | 0.76 | APP (0.48) | CA12CA1CA2CA4CA9 | |
| SCHEMBL853691 | 0.76 | CYP2A6 (0.48) | HDAC8CA12CA2CA9CA14 | |
| SCHEMBL4736294 | 0.76 | GABRA1 (0.37) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9650374-B2 | Photochromic tetrahydroindolizines | UMM AL-QURA UNIVERSITY (SA) | 2017-05-16 | — | — | US | disclosed |
| US-20160122338-A1 | NOVEL PHOTOCHROMIC TETRAHYDROINDOLIZINES | UMM AL-QURA UNIVERSITY (SA) | 2016-05-05 | — | — | US | disclosed |
| US-20150198552-A9 | NOVEL CHEMISTRY USED IN BIOSENSORS | OHMX CORPORATION (US) | 2015-07-16 | — | — | US | disclosed |
| US-8951400-B2 | Chemistry used in biosensors | OHMX CORPORATION (US) | 2015-02-10 | — | — | US | disclosed |
| US-20140311922-A1 | NOVEL CHEMISTRY USED IN BIOSENSORS | OHMX CORPORATION (US) | 2014-10-23 | — | — | US | disclosed |
| US-8734631-B2 | Chemistry used in biosensors | OHMX CORPORATION (US) | 2014-05-27 | — | — | US | disclosed |
| WO-2012012537-A1 | NOVEL CHEMISTRY USED IN BIOSENSORS | OHMX CORPORATION (US) | 2012-01-26 | — | — | WO | disclosed |
| US-20120012472-A1 | NOVEL CHEMISTRY USED IN BIOSENSORS | OHMX CORPORATION (US) | 2012-01-19 | — | — | US | disclosed |
| EP-2210268-A1 | NOVEL CHEMISTRY USED IN BIOSENSORS | Ohmx Corporation (US) | 2010-07-28 | — | — | EP | disclosed |
| US-20090253149-A1 | Novel Chemistry Used in Biosensors | OHMX CORPORATION (US) | 2009-10-08 | — | — | US | disclosed |
| WO-2009052436-A1 | NOVEL CHEMISTRY USED IN BIOSENSORS | OHMX CORPORATION (US) | 2009-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160122338-A1 | NOVEL PHOTOCHROMIC TETRAHYDROINDOLIZINES | DHPS, TPH2, DHX15 | HDAC8 1807/4885KEAP1 75/4885CA12 2970/4885 |
| US-20120012472-A1 | NOVEL CHEMISTRY USED IN BIOSENSORS | SSBP1, OSGEP, OCIAD2 | HDAC8 4350/4885KEAP1 4173/4885CA12 1534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.