Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL122137 | 0.85 | ALOX15 (0.42) | ALOX15ITGB3ITGA2BTSHRGNAI3 | |
| Hydrochloric Acid SCHEMBL26599945 | 0.84 | GNAI3 (0.43) | ALOX15ITGB3ITGA2BTSHRGNAI3 | |
| Trifluoroacetic Acid SCHEMBL4007510 | 0.78 | ALOX15 (0.53) | ALOX15F2TSHRCHRM3GNAI3 | |
| Trifluoroacetic Acid SCHEMBL3522640 | 0.76 | ALOX15 (0.47) | ALOX15ITGB3ITGA2BF2TSHR | |
| Trifluoroacetic Acid SCHEMBL4355414 | 0.76 | EPHX1 (0.40) | ITGB3ITGA2BTSHRGNAI3GNAO1 | |
| SCHEMBL321293 | 0.75 | GABRA5 (0.41) | ALOX15TSHRGNAI3GNAO1GNAI1 | |
| SCHEMBL1348800 | 0.75 | GABRA5 (0.41) | ALOX15TSHRGNAI3GNAO1GNAI1 | |
| SCHEMBL10059949 | 0.75 | GABRA5 (0.41) | ALOX15TSHRGNAI3GNAO1GNAI1 | |
| Trifluoroacetic Acid SCHEMBL30931805 | 0.74 | GABRA5 (0.38) | ITGB3ITGA2BF2TSHRCHRM3 | |
| Trifluoroacetic Acid SCHEMBL28974434 | 0.74 | GABRA1 (0.40) | ITGB3ITGA2BTSHRGNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101684091-A | cannabinoid receptor ligands | SCHERING CORP | 2010-03-31 | — | — | CN | disclosed |
| US-7645774-B2 | Cannabinoid receptor ligands | SCHERING CORPORATION (US) | 2010-01-12 | — | — | US | disclosed |
| CN-100567266-C | Cannabinoid receptor ligands | SCHERING CORP (US) | 2009-12-09 | — | — | CN | disclosed |
| US-7071213-B2 | Cannabinoid receptor ligands | SCHERING CORPORATION (US) | 2006-07-04 | — | — | US | disclosed |
| US-20050282861-A1 | Cannabinoid receptor ligands | MERCK SHARP & DOHME CORP. | 2005-12-22 | — | — | US | disclosed |
| CN-1585749-A | Cannabinoid receptor ligands | SCHERING CORP (US) | 2005-02-23 | — | — | CN | disclosed |
| EP-1444203-A1 | CANNABINOID RECEPTOR LIGANDS | Schering Corporation (US) | 2004-08-11 | — | — | EP | disclosed |
| US-20040010013-A1 | Piperidine derivatives used in treating cancer, inflammatory diseases, immunomodulatory diseases, or respiratory diseases | SCHERING CORPORATION | 2004-01-15 | — | — | US | disclosed |
| WO-2003042174-A1 | CANNABINOID RECEPTOR LIGANDS | SCHERING CORPORATION (US) | 2003-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040010013-A1 | Piperidine derivatives used in treating cancer, inflammatory diseases, immunomodulatory diseases, or respiratory diseases | IL5, IL2, TLR1 | ALOX15 903/4885ITGB3 3957/4885ITGA2B 3307/4885 |
| US-20050282861-A1 | Cannabinoid receptor ligands | CNR1, CNR2, GPR18 | ALOX15 695/4885ITGB3 2171/4885ITGA2B 2050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.