Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 3/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10278375 | 0.94 | ADRA1B (0.48) | HTR7ATMADRA1AADRB1DRD2 | |
| SCHEMBL14067200 | 0.81 | HTR7 (0.59) | HTR7ATMADRA1AADRB1ADRA1D | |
| SCHEMBL3551183 | 0.81 | ALDH1A1 (0.61) | ADRA1ADRD2DRD3ADRA1BKMT2A | |
| SCHEMBL3553897 | 0.81 | IGF1R (0.53) | DRD2MAPTGAAHTT | |
| SCHEMBL4291189 | 0.80 | ADRB1 (0.72) | HTR7ATMADRA1AADRB1ADRA1D | |
| SCHEMBL12126914 | 0.79 | GAA (0.58) | HTR7ATMADRA1AADRB1DRD2 | |
| SCHEMBL3552347 | 0.78 | DRD2 (0.47) | DRD2DRD3KMT2AHTT | |
| SCHEMBL3552481 | 0.78 | ALDH1A1 (0.47) | KMT2AGAA | |
| SCHEMBL3546173 | 0.78 | DRD2 (0.51) | DRD2DRD3KMT2ALMNAMAPT | |
| SCHEMBL7289302 | 0.78 | DRD2 (0.58) | HTR7ATMADRA1AADRB1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163746-B2 | Azolecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | GPR17, NTRK1, TRPV1 | HTR7 1361/4885ATM 1967/4885ADRA1A 135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.