SCHEMBL35531

SCHEMBL35531

C=CN1CCCC(C)C1=O

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.35
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM5 P08912 1/20 0.35
CHRM1 P11229 1/20 0.35
CHRM3 P20309 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA4 P22748 1/20 0.34
KMT2A Q03164 1/20 0.33
PER2 O15055 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL996315 0.94 CHRM2 (0.38) PIK3CDCHRM2CHRM4CHRM5CHRM1
SCHEMBL195053 0.88
SCHEMBL868162 0.77 PIK3CD (0.30) PIK3CD
SCHEMBL3142692 0.77 CHRM2 (0.32) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL2367887 0.76 PER2 (0.34) PER2
SCHEMBL10033658 0.74
SCHEMBL867834 0.72 PIK3CD (0.33) PIK3CD
SCHEMBL29076626 0.72 NOS1 (0.41) KMT2A
SCHEMBL10410365 0.71 BRD4 (0.39) PIK3CDKMT2A
SCHEMBL868086 0.71 CA1 (0.38) PIK3CDCHRM2CHRM4CHRM5CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1904 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12638614-B2 Method for making silicone hydrogel contact lenses ALCON INC. (CH) 2026-05-26 US claimed
US-20260131506-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-05-14 US claimed
US-12595368-B2 UV/HEVL-filtering contact lenses ALCON INC. (CH) 2026-04-07 US claimed
EP-4713721-A1 UV/HEVL-FILTERING SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-03-25 EP claimed
EP-4707315-A1 COPOLYMER, COMPOSITION AND USE THEREOF Beijing Mapu New Materials Co., Ltd. (CN) 2026-03-11 EP claimed
US-12570784-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-03-10 US claimed
EP-3759528-B1 SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-03-04 EP claimed
EP-4514596-B1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-03-04 EP claimed
US-12539650-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-02-03 US claimed
US-20250347826-A1 METHOD FOR PRODUCING WETTABLE SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2025-11-13 US claimed
US-6558688-B2 Ocular tissue regeneration inducer KURARAY CO., LTD. (JP) 2003-05-06 US claimed
WO-2003022321-A2 BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS JOHNSON & JOHNSON VISION CARE, INC. (US) 2003-03-20 WO claimed
WO-2003022322-A2 BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS JOHNSON & JOHNSON VISION CARE, INC. (US) 2003-03-20 WO claimed
US-20010038860-A1 Ocular tissue regeneration inducer KURARAY CO., LTD.; (JP) 2001-11-08 US claimed
CN-1283280-A Actively controllable multifocal lens NOVARTIS AG (CH) 2001-02-07 CN claimed
EP-1044389-A2 ACTIVELY CONTROLLABLE MULTIFOCAL LENS Novartis AG (CH) 2000-10-18 EP claimed
US-5997140-A Actively controllable multifocal lens NOVARTIS AG (CH) 1999-12-07 US claimed
WO-1999034239-A2 ACTIVELY CONTROLLABLE MULTIFOCAL LENS NOVARTIS AG (CH) 1999-07-08 WO claimed
US-4123408-A Hydrogel contact lens AMERICAN OPTICAL CORPORATION (US) 1978-10-31 US claimed
US-4123407-A Hydrophilic contact lens AMERICAN OPTICAL CORPORATION (US) 1978-10-31 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12539650-B2 Method for making embedded hydrogel contact lenses INF2, CRYZ, CRYAA PIK3CD 3256/4885CHRM2 1921/4885CHRM4 2315/4885
US-12595368-B2 UV/HEVL-filtering contact lenses UACA, HSPA4L, RAD54L PIK3CD 4850/4885CHRM2 2947/4885CHRM4 2134/4885
US-12570784-B2 Method for making embedded hydrogel contact lenses CRYAB, CRYZ, CRYAA PIK3CD 1516/4885CHRM2 1546/4885CHRM4 2718/4885
US-12638614-B2 Method for making silicone hydrogel contact lenses SMCHD1, CRYAA, CRYZ PIK3CD 1970/4885CHRM2 1662/4885CHRM4 1278/4885
US-20260131506-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES CRYZ, CRYAB, CRYAA PIK3CD 3755/4885CHRM2 2458/4885CHRM4 2597/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.