SCHEMBL3554144

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3549203	0.82	ESR1 (0.49)	L3MBTL1ALDH1A1GAAESR1ESR2
	SCHEMBL3549201	0.82	ESR1 (0.49)	L3MBTL1ALDH1A1GAAESR1ESR2
	SCHEMBL28017822	0.80	L3MBTL1 (0.62)	L3MBTL1ALDH1A1GAAESR1ESR2
	SCHEMBL6461974	0.80	L3MBTL1 (0.62)	L3MBTL1ALDH1A1GAAESR1ESR2
	SCHEMBL3873604	0.77	ESR1 (0.50)	L3MBTL1ALDH1A1GAAESR1ESR2
	SCHEMBL3667647	0.77	ESR1 (0.50)	L3MBTL1ALDH1A1GAAESR1ESR2
	SCHEMBL3725347	0.77	ESR1 (0.50)	L3MBTL1ALDH1A1GAAESR1ESR2
	SCHEMBL12352461	0.77	ESR1 (0.42)	ESR1ESR2LMNATDP1HSD17B10
	SCHEMBL22668298	0.77	MMP9 (0.54)	L3MBTL1ALDH1A1GAAESR1ESR2
	SCHEMBL7603467	0.76	L3MBTL1 (0.46)	L3MBTL1ALDH1A1GAAESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.