SCHEMBL3561516

SCHEMBL3561516

Bc1scc(C2CCCCC2)c1C

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 2/20 0.36
PSMB5 P28074 1/20 0.32
TDO2 P48775 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3561513 0.77 GPR35 (0.36) GPR35PSMB5TDO2
SCHEMBL3557120 0.77 GPR35 (0.36) GPR35PSMB5TDO2
SCHEMBL3558293 0.73 GPR35 (0.36) GPR35PSMB5
SCHEMBL13502106 0.67 P2RX7 (0.32) GPR35
SCHEMBL146043 0.65 PSMB5 (0.38) PSMB5TDO2
SCHEMBL143816 0.65 TDO2 (0.39) PSMB5TDO2
SCHEMBL31240954 0.64 HTR2C (0.52) PSMB5
SCHEMBL4580554 0.64 ALDH1A1 (0.42) PSMB5TDO2
SCHEMBL28849763 0.64 ALDH1A1 (0.42) PSMB5TDO2
SCHEMBL9167795 0.63 PSMB5 (0.46) PSMB5TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7663301-B2 for use as robust red organic phosphors GENERAL ELECTRIC COMPANY (US) 2010-02-16 US disclosed
WO-2006076247-A2 PHOSPHORESCENT FLUORENE, ANTHRACENE AND/OR THIOPHENE SUBSTITUTED METALLO- PORPHYRINS AND RELATED COMPOUNDS GENERAL ELECTRIC COMPANY (US) 2006-07-20 WO disclosed
US-20060152149-A1 Porphyrin compositions GENERAL ELECTRIC COMPANY (US) 2006-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060152149-A1 Porphyrin compositions ACP1, MMS19, MVD GPR35 3198/4885PSMB5 3272/4885TDO2 276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.