SCHEMBL3565689

SCHEMBL3565689

CC(=O)c1ccc(C(=O)ON2C(=O)CCC2=O)cc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.42
HPGD P15428 3/20 0.42
RAB9A P51151 2/20 0.42
ALDH1A1 P00352 2/20 0.40
KMT2A Q03164 6/20 0.40
SLC6A3 Q01959 1/20 0.40
ADAM17 P78536 1/20 0.40
L3MBTL1 Q9Y468 3/20 0.39
LMNA P02545 2/20 0.38
NPC1 O15118 1/20 0.38
MEN1 O00255 1/20 0.38
TP53 P04637 1/20 0.37
HSD17B1 P14061 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA9 Q16790 1/20 0.37
GAA P10253 1/20 0.37
GLA P06280 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28736317 0.94 CA1 (0.47) MAPTHPGDRAB9AALDH1A1KMT2A
SCHEMBL300884 0.91 CA12 (0.42) MAPTHPGDRAB9AALDH1A1KMT2A
SCHEMBL19150003 0.89 HPGD (0.37) MAPTHPGDRAB9AALDH1A1KMT2A
SCHEMBL14640220 0.86 ALDH1A1 (0.54) MAPTHPGDALDH1A1KMT2AMEN1
SCHEMBL8433813 0.86 KMT2A (0.50) MAPTHPGDRAB9AALDH1A1KMT2A
SCHEMBL13455758 0.85 SMN1; SMN2 (0.44) HPGDRAB9AALDH1A1KMT2ALMNA
SCHEMBL5648489 0.84 CA12 (0.47) MAPTHPGDRAB9AALDH1A1KMT2A
SCHEMBL4393639 0.83 TSHR (0.45) ALDH1A1KMT2ALMNAMEN1
SCHEMBL7740161 0.83 CA1 (0.55) MAPTHPGDALDH1A1KMT2AMEN1
SCHEMBL21998937 0.83 MAPT (0.40) MAPTHPGDRAB9AALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12497417-B2 Delivery systems for controlled drug release LADRX CORPORATION (US) 2025-12-16 US disclosed
US-20230023537-A1 DELIVERY SYSTEMS FOR CONTROLLED DRUG RELEASE LADRX CORPORATION 2023-01-26 US disclosed
CN-115089722-A Delivery system for controlled drug release 森托瑞恩生物制药公司 2022-09-23 CN disclosed
US-11384104-B2 Delivery systems for controlled drug release CENTURION BIOPHARMA CORPORATION (US) 2022-07-12 US disclosed
CN-107922457-B Delivery system for controlled drug release 森托瑞恩生物制药公司 2022-05-13 CN disclosed
EP-3954394-A1 DELIVERY SYSTEMS FOR CONTROLLED DRUG RELEASE Centurion BioPharma Corporation (US) 2022-02-16 EP disclosed
EP-3310800-B1 DELIVERY SYSTEMS FOR CONTROLLED DRUG RELEASE CENTURION BIOPHARMA CORP (US) 2021-11-17 EP disclosed
US-20210325376-A1 POLYMERS AND CONJUGATES COMPRISING THE SAME VENTANA MED SYST INC (US) 2021-10-21 US disclosed
US-11079372-B2 Polymers and conjugates comprising the same VENTANA MEDICAL SYSTEMS, INC. (US) 2021-08-03 US disclosed
US-10696699-B2 Charged linkers and their uses for conjugation HANGZHOU DAC BIOTECH CO., LTD. (CN) 2020-06-30 US disclosed
US-6911535-B2 Covalently linking natural or synthetic biomolecule to a mono-or bi-functional polymer; covalently and/or electrostatically immobilizing biomolecule/polymer conjugate to a unmodified or modified surface SOLVLINK BIOSCIENCES (US) 2005-06-28 US disclosed
EP-1351991-A4 TERNARY BIOMOLECULE/POLYMER/SURFACE-BASED IMMOBILIZATION SYSTEMS SCHWARTZ DAVID A (US) 2004-12-01 EP disclosed
US-20040214199-A1 Triphosphate oligonucleotide modification reagents and uses thereof AUDAX PRIVATE DEBT LLC, AS AGENT 2004-10-28 US disclosed
US-6686461-B1 HYDRAZINO, OXYAMINO AND CARBONYL-BASED MONOMERS AND METHODS FOR LABELLING OF OLIGONUCLEOTIDES WITHOUT THE NEED FOR POST-SYNTHETIC MODIFICATION SOLULINK BIOSCIENCE, INC. 2004-02-03 US disclosed
EP-1351991-A2 TERNARY BIOMOLECULE/POLYMER/SURFACE-BASED IMMOBILIZATION SYSTEMS Schwartz, David A. (US) 2003-10-15 EP disclosed
EP-1305327-A2 TRIPHOSPHATE OLIGONUCLEOTIDE MODIFICATION REAGENTS AND USES THEREOF Schwartz, David A. (US) 2003-05-02 EP disclosed
US-20020146504-A1 Ternary biomolecule/polymer/surface-based immobilization systems AUDAX PRIVATE DEBT LLC, AS AGENT 2002-10-10 US disclosed
WO-2002057422-A2 TERNARY BIOMOLECULE/POLYMER/SURFACE-BASED IMMOBILIZATION SYSTEMS SCHWARTZ DAVID A (US) 2002-07-25 WO disclosed
WO-2002010432-A2 TRIPHOSPHATE OLIGONUCLEOTIDE MODIFICATION REAGENTS AND USES THEREOF SCHWARTZ DAVID A (US) 2002-02-07 WO disclosed
WO-2002010431-A2 FUNCTIONAL BIOPOLYMER MODIFICATION REAGENTS AND USES THEREOF SCHWARTZ DAVID A (US) 2002-02-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020146504-A1 Ternary biomolecule/polymer/surface-based immobilization systems EPCAM, DNPEP, ANPEP MAPT 4178/4885HPGD 3801/4885RAB9A 4795/4885
US-11384104-B2 Delivery systems for controlled drug release ABCB11, SLC10A1, SLC5A1 MAPT 565/4885HPGD 662/4885RAB9A 1629/4885
US-20040214199-A1 Triphosphate oligonucleotide modification reagents and uses thereof RNGTT, DUT, NUDT1 MAPT 4128/4885HPGD 793/4885RAB9A 4795/4885
US-20230023537-A1 DELIVERY SYSTEMS FOR CONTROLLED DRUG RELEASE ABCB11, SLC10A1, SLC5A1 MAPT 565/4885HPGD 662/4885RAB9A 1629/4885
US-12497417-B2 Delivery systems for controlled drug release ABCB11, SLC10A1, SLC5A1 MAPT 565/4885HPGD 662/4885RAB9A 1629/4885
US-10696699-B2 Charged linkers and their uses for conjugation PHOSPHO1, PCTP, CD2BP2 MAPT 3444/4885HPGD 3704/4885RAB9A 1185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.