Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | VNN1 | O95497 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3581450 | 0.91 | MEP1B (0.41) | LPAR1LPAR5PPARGPPARANR1H4 | |
| SCHEMBL3579507 | 0.87 | HDAC8 (0.41) | PPARGPPARANR1H4KMT2ASLC2A1 | |
| SCHEMBL3581545 | 0.84 | CNR1 (0.40) | TRPM8LPAR1LPAR5PPARGPPARD | |
| SCHEMBL3586145 | 0.82 | CNR1 (0.42) | KDM5AKDM4CKDM5BTRPM8LPAR1 | |
| SCHEMBL3575602 | 0.82 | LPAR1 (0.38) | LPAR1LPAR5PPARGEPHX2NR1H4 | |
| SCHEMBL3583813 | 0.81 | CNR1 (0.41) | KDM5AKDM4CKDM5BLPAR1LPAR5 | |
| SCHEMBL3581404 | 0.81 | CNR1 (0.43) | KDM5AKDM4CKDM5BLPAR1LPAR5 | |
| SCHEMBL3575452 | 0.81 | KMT2A (0.42) | PPARGPPARANR1H4KMT2A | |
| SCHEMBL3583799 | 0.81 | CNR1 (0.40) | KDM5AKDM4CKDM5BTRPM8LPAR1 | |
| SCHEMBL3569982 | 0.81 | LPAR1 (0.41) | LPAR1LPAR5PPARGNR1H4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |