Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.44 |
| ▸ | DPP4 | P27487 | 9/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3600416 | 0.83 | CNR1 (0.42) | CNR1DPP4DPP8 | |
| SCHEMBL3605612 | 0.83 | CNR1 (0.43) | CNR1DPP4DPP8CYP3A4CYP1A2 | |
| SCHEMBL3601694 | 0.83 | BCL2L2 (0.45) | DPP4DPP8CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL3084453 | 0.82 | CNR1 (0.45) | CNR1DPP4DPP8CYP3A4DPP9 | |
| SCHEMBL3602324 | 0.81 | CYP11B1 (0.41) | CNR1DPP4DPP8SMN1; SMN2P2RX7 | |
| SCHEMBL3593028 | 0.81 | ALDH1A1 (0.44) | CNR1DPP4DPP8CYP3A4CYP2C19 | |
| SCHEMBL3600972 | 0.80 | DPP4 (0.41) | CNR1DPP4DPP8CYP3A4CYP1A2 | |
| SCHEMBL3605710 | 0.79 | MEN1 (0.40) | CNR1DPP4DPP8CYP3A4CYP1A2 | |
| SCHEMBL3089159 | 0.77 | CNR1 (0.40) | CNR1DPP4DPP8P2RX7TP53 | |
| SCHEMBL3600935 | 0.77 | TP53 (0.45) | DPP4DPP8CYP3A4CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728146-B2 | Enzyme inhibitors | PROBIODRUG AG (DE) | 2010-06-01 | — | — | US | claimed |