Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3593028 | 0.89 | ALDH1A1 (0.44) | DPP4KCNH2ALDH1A1DPP8CYP3A4 | |
| SCHEMBL3600416 | 0.87 | CNR1 (0.42) | DPP4KCNH2DPP8CNR1MDM4 | |
| SCHEMBL3598037 | 0.87 | CXCR2 (0.47) | DPP4MEN1KMT2AALDH1A1DPP8 | |
| SCHEMBL3596602 | 0.85 | TTR (0.40) | DPP4MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL3592478 | 0.83 | P2RX7 (0.44) | DPP4ALDH1A1DPP8MDM4MDM2 | |
| SCHEMBL3602324 | 0.83 | CYP11B1 (0.41) | DPP4MEN1KMT2AALDH1A1DPP8 | |
| SCHEMBL3605612 | 0.82 | CNR1 (0.43) | DPP4DPP8HTTSMN1; SMN2CYP3A4 | |
| SCHEMBL3091436 | 0.82 | DPP4 (0.46) | DPP4KCNH2MEN1KMT2AALDH1A1 | |
| SCHEMBL3595008 | 0.82 | CXCR2 (0.50) | DPP4LMNAHTTTSHRTP53 | |
| SCHEMBL3600935 | 0.81 | TP53 (0.45) | DPP4ALDH1A1DPP8LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728146-B2 | Enzyme inhibitors | PROBIODRUG AG (DE) | 2010-06-01 | — | — | US | claimed |