Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3601694 | 0.88 | BCL2L2 (0.45) | CYP3A4CYP1A2CYP2D6TSHRCYP2C19 | |
| SCHEMBL3598037 | 0.86 | CXCR2 (0.47) | MEN1KMT2AHSP90AA1HSP90AB1CYP3A4 | |
| SCHEMBL3595101 | 0.85 | DPP4 (0.43) | MEN1KMT2AHSP90AA1HSP90AB1NR3C2 | |
| SCHEMBL3595008 | 0.83 | CXCR2 (0.50) | TSHRDPP4HSD17B10CXCR2MAPT | |
| SCHEMBL3596602 | 0.82 | TTR (0.40) | MEN1KMT2ADPP4CXCR2CNR1 | |
| SCHEMBL3605612 | 0.80 | CNR1 (0.43) | CYP3A4CYP1A2CYP2D6TSHRCYP2C19 | |
| SCHEMBL3597074 | 0.79 | CNR1 (0.44) | CYP3A4CYP1A2CYP2D6TSHRCYP2C19 | |
| SCHEMBL3602324 | 0.78 | CYP11B1 (0.41) | MEN1KMT2ADPP4ALDH1A1KDM4E | |
| SCHEMBL3593028 | 0.77 | ALDH1A1 (0.44) | CYP3A4CYP2C19DPP4ALDH1A1CXCR2 | |
| SCHEMBL3600972 | 0.76 | DPP4 (0.41) | MEN1KMT2ACYP3A4CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728146-B2 | Enzyme inhibitors | PROBIODRUG AG (DE) | 2010-06-01 | — | — | US | claimed |