Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.45 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3605612 | 0.88 | CNR1 (0.43) | DPP4P2RX7CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3605710 | 0.88 | MEN1 (0.40) | DPP4KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3602324 | 0.86 | CYP11B1 (0.41) | DPP4P2RX7KDM4ETP53ALDH1A1 | |
| SCHEMBL3089977 | 0.84 | BCL2L2 (0.50) | BCL2L2YTHDC1DPP4P2RX7TAAR1 | |
| SCHEMBL3593028 | 0.83 | ALDH1A1 (0.44) | DPP4TP53CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL3596602 | 0.83 | TTR (0.40) | YTHDC1DPP4SMN1; SMN2 | |
| SCHEMBL3597074 | 0.83 | CNR1 (0.44) | DPP4P2RX7TP53CYP1A2CYP3A4 | |
| SCHEMBL3598037 | 0.82 | CXCR2 (0.47) | DPP4TP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL3595008 | 0.80 | CXCR2 (0.50) | YTHDC1DPP4P2RX7TAAR1ADORA2A | |
| SCHEMBL3599723 | 0.80 | CNR1 (0.42) | DPP4TAAR1TP53CYP3A4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728146-B2 | Enzyme inhibitors | PROBIODRUG AG (DE) | 2010-06-01 | — | — | US | claimed |