SCHEMBL359732

SCHEMBL359732

Ic1ccc2ncccc2c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.63
POLB P06746 2/20 0.63
RAB9A P51151 2/20 0.63
ALDH1A1 P00352 5/20 0.59
MAPT P10636 4/20 0.59
HTT P42858 3/20 0.59
ATM Q13315 2/20 0.59
KDM4E B2RXH2 2/20 0.59
CASP1 P29466 2/20 0.59
TP53 P04637 1/20 0.59
HSP90AA1 P07900 1/20 0.59
HSP90AB1 P08238 1/20 0.59
TSHR P16473 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
HSD17B10 Q99714 1/20 0.59
DYRK1A Q13627 1/20 0.50
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
CASP3 P42574 1/20 0.47
SENP7 Q9BQF6 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3282314 0.83 ALDH1A1 (0.59) NPC1POLBRAB9AALDH1A1MAPT
SCHEMBL19366747 0.79 NPC1 (0.39) NPC1POLBRAB9AALDH1A1MAPT
SCHEMBL29757180 0.77 NPC1 (1.00) NPC1POLBRAB9AALDH1A1MAPT
SCHEMBL30743 0.77 NPC1 (1.00) NPC1POLBRAB9AALDH1A1MAPT
SCHEMBL29350099 0.76 NPC1 (0.65) NPC1POLBRAB9AALDH1A1MAPT
SCHEMBL150476 0.76 NPC1 (0.65) NPC1POLBRAB9AALDH1A1MAPT
SCHEMBL3694131 0.76 NPC1 (0.65) NPC1POLBRAB9AALDH1A1MAPT
SCHEMBL18848442 0.76 NPC1 (0.54) NPC1POLBRAB9AALDH1A1MAPT
SCHEMBL21507918 0.76 NPC1 (0.65) NPC1POLBRAB9AALDH1A1MAPT
SCHEMBL4783245 0.74 NPC1 (0.63) NPC1POLBRAB9AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 490 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120158196-A Water-based anticorrosive paint and preparation method thereof 海南智筑新型建筑材料科技有限公司 2025-06-17 CN claimed
CN-115057803-A S- (methyl-d) 3 ) Synthetic method and application of phenylether substances 杭州师范大学 2022-09-16 CN claimed
US-3960566-A Method for dry stabilization of silver halide photographic material FUJI PHOTO FILM CO., LTD. (JA) 1976-06-01 US claimed
EP-4678632-A1 METHOD FOR PRODUCING ARYL COMPOUND CONTAINING TRITYLSULFANYL GROUP AGC Inc. (JP) 2026-01-14 EP disclosed
EP-4665718-A1 SMALL MOLECULES AS MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS, COMPOSITIONS AND USE THEREOF Apogee Pharmaceuticals, Inc. (CA) 2025-12-24 EP disclosed
US-20250346557-A1 METHOD FOR PRODUCING ARYL COMPOUND CONTAINING TRITYLSULFANYL GROUP AGC Inc. (JP) 2025-11-13 US disclosed
US-12378231-B2 Small molecules as monoacylglycerol lipase (MAGL) inhibitors, compositions and use thereof APOGEE PHARMACEUTICALS, INC. (CA) 2025-08-05 US disclosed
CN-120158196-A Water-based anticorrosive paint and preparation method thereof 海南智筑新型建筑材料科技有限公司 2025-06-17 CN disclosed
CN-120004934-A Preparation method of benzo-silicon-containing octatomic ring compound 郑州大学 2025-05-16 CN disclosed
US-12291504-B2 Small molecule inhibition of sulfotransferase SULT1A3 University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2025-05-06 US disclosed
CN-119775089-A Hydrodehalogenation method for catalyzing halohydrocarbon by using bidentate nitrogen ligand palladium complex 浙江工业大学 2025-04-08 CN disclosed
EP-1601357-A1 HETEROCYCLIC KINASE INHIBITORS: METHODS OF USE AND SYNTHESIS SCHERING CORPORATION (US) 2005-12-07 EP disclosed
US-20050064510-A1 Ligand analysis NEOGENESIS PHARMACEUTICALS, INC. 2005-03-24 US disclosed
WO-2004081531-A9 LIGAND ANALYSIS NEOGENESIS PHARMACEUTICALS INC (US) 2004-10-28 WO disclosed
WO-2004081531-A2 LIGAND ANALYSIS SCHERING CORPORATION (US) 2004-09-23 WO disclosed
WO-2004080463-A1 HETEROCYCLIC KINASE INHIBITORS: METHODS OF USE AND SYNTHESIS SCHERING CORPORATION (US) 2004-09-23 WO disclosed
EP-0088595-B1 CYANINE DYES FOR SENSITIZING SILVER HALIDE EMULSIONS TO INFRARED RADIATION AND PHOTOGRAPHIC ELEMENTS INCLUDING THEM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-09-24 EP disclosed
US-4515888-A BASED ON 5-METHYL-6-METHOXYBENZOTHIAZOLE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-05-07 US disclosed
EP-0088595-A2 Cyanine dyes for sensitizing silver halide emulsions to infrared radiation and photographic elements including them MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-09-14 EP disclosed
US-3960566-A Method for dry stabilization of silver halide photographic material FUJI PHOTO FILM CO., LTD. (JA) 1976-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12378231-B2 Small molecules as monoacylglycerol lipase (MAGL) inhibitors, compositions and use thereof MGLL, PNLIP, LPL NPC1 602/4885POLB 760/4885RAB9A 665/4885
US-20250346557-A1 METHOD FOR PRODUCING ARYL COMPOUND CONTAINING TRITYLSULFANYL GROUP STS, TST, CYP3A5 NPC1 1421/4885POLB 4818/4885RAB9A 2586/4885
US-12291504-B2 Small molecule inhibition of sulfotransferase SULT1A3 SULT1A1, SULT2A1, SULT1E1 NPC1 3742/4885POLB 2032/4885RAB9A 3480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.