Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MDM4 | O15151 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3595829 | 0.89 | CYP3A4 (0.44) | MARS1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3593028 | 0.86 | ALDH1A1 (0.44) | MARS1GAACYP3A4CYP2C19CRHR1 | |
| SCHEMBL3605612 | 0.84 | CNR1 (0.43) | ADRA1DCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3602324 | 0.82 | CYP11B1 (0.41) | KMT2AMEN1GAAALDH1A1DPP4 | |
| SCHEMBL3102939 | 0.82 | DPP4 (0.47) | MARS1KMT2AMEN1GAAADRA1D | |
| SCHEMBL3600972 | 0.81 | DPP4 (0.41) | KMT2AMEN1GAALMNACYP1A2 | |
| SCHEMBL3592478 | 0.81 | P2RX7 (0.44) | MARS1ADRA1DHRH1ALDH1A1DPP4 | |
| SCHEMBL3601694 | 0.80 | BCL2L2 (0.45) | CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL3594733 | 0.79 | CXCR2 (0.44) | GAAADRA1DCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3600935 | 0.78 | TP53 (0.45) | LMNACYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728146-B2 | Enzyme inhibitors | PROBIODRUG AG (DE) | 2010-06-01 | — | — | US | claimed |