Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | LPO | P22079 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3598037 | 0.89 | CXCR2 (0.47) | CXCR2LMNADPP4TP53IDO1 | |
| SCHEMBL3593028 | 0.87 | ALDH1A1 (0.44) | CXCR2DPP4TP53 | |
| SCHEMBL3091438 | 0.84 | CXCR2 (0.51) | CXCR2HTTYTHDC1P2RX7LMNA | |
| SCHEMBL3596602 | 0.84 | TTR (0.40) | CXCR2YTHDC1LMNADPP4ROCK2 | |
| SCHEMBL3605710 | 0.83 | MEN1 (0.40) | CXCR2LMNADPP4MAPTTSHR | |
| SCHEMBL3600972 | 0.82 | DPP4 (0.41) | HTTLMNADPP4TP53IDO1 | |
| SCHEMBL3592478 | 0.81 | P2RX7 (0.44) | P2RX7DPP4ADRA1DIDO1 | |
| SCHEMBL3600416 | 0.81 | CNR1 (0.42) | DPP4 | |
| SCHEMBL3601694 | 0.80 | BCL2L2 (0.45) | YTHDC1P2RX7DPP4TAAR1TP53 | |
| SCHEMBL3595338 | 0.79 | PNMT (0.41) | CXCR2HTTYTHDC1LMNADPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728146-B2 | Enzyme inhibitors | PROBIODRUG AG (DE) | 2010-06-01 | — | — | US | claimed |