SCHEMBL360266

SCHEMBL360266

ClCc1cccnc1CCl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
DPP4 P27487 1/20 0.35
KDM4E B2RXH2 4/20 0.34
KMT2A Q03164 3/20 0.34
MAPT P10636 3/20 0.34
CYP1A2 P05177 1/20 0.34
TSHR P16473 2/20 0.33
CASP3 P42574 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
BACE1 P56817 1/20 0.33
TDP1 Q9NUW8 2/20 0.32
HIF1A Q16665 2/20 0.32
GMNN O75496 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
HSP90AA1 P07900 1/20 0.32
MMP2 P08253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29900533 1.00 ALDH1A1 (0.40) ALDH1A1L3MBTL1DPP4KDM4EKMT2A
Hydrochloric Acid SCHEMBL1856795 0.98 ALDH1A1 (0.39) ALDH1A1L3MBTL1DPP4KDM4EKMT2A
Hydrochloric Acid SCHEMBL1856799 0.98 ALDH1A1 (0.39) ALDH1A1L3MBTL1DPP4KDM4EKMT2A
SCHEMBL7347316 0.85 ALDH1A1 (0.36) ALDH1A1L3MBTL1DPP4KDM4EKMT2A
SCHEMBL27341970 0.85 ALDH1A1 (0.36) ALDH1A1L3MBTL1DPP4KDM4EKMT2A
SCHEMBL28906832 0.85 ALDH1A1 (0.36) ALDH1A1L3MBTL1DPP4KDM4EKMT2A
SCHEMBL20831662 0.85 GABRA1 (0.37) ALDH1A1L3MBTL1KDM4EMAPTCYP1A2
SCHEMBL4670154 0.85 L3MBTL1 (0.50) ALDH1A1L3MBTL1KDM4EKMT2AMAPT
Hydrochloric Acid SCHEMBL20817972 0.83 ALDH1A1 (0.35) ALDH1A1L3MBTL1DPP4KDM4ECASP3
Hydrochloric Acid SCHEMBL6574392 0.83 L3MBTL1 (0.48) ALDH1A1L3MBTL1KDM4EKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109705116-A A kind of synthetic method of 6- benzyl-pyrrole simultaneously [3,4-b] pyridine 赵明 2019-05-03 CN claimed
WO-2008027479-A2 HIGHLY ACTIVE ALPHA-OLEFIN COPOLYMERIZATION CATALYST SYSTEM FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2008-03-06 WO claimed
EP-1087834-A1 HIGH PERFORMANCE COMPOSITE MEMBRANE KOCH MEMBRANE SYSTEMS, INC (US) 2001-04-04 EP claimed
US-6132804-A COATING SUBSTRATE WITH LIQUID COMPONENT TO FORM LIQUID LAYER; COATING SECOND LIQUID; ALLOWING THE LIQUIDS TO INTERFACIALLY POLYMERIZE TO FORM COMPOSITE LAYER; DRYING TO FORM COMPOSITE MEMBRANE KOCH MEMBRANE SYSTEMS, INC. (US) 2000-10-17 US claimed
WO-1999062623-A1 HIGH PERFORMANCE COMPOSITE MEMBRANE KOCH MEMBRANE SYSTEMS, INC. (US) 1999-12-09 WO claimed
US-12241902-B2 Probes for detection of copper THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-03-04 US disclosed
US-20240262792-A1 USP30 INHIBITORS AND USES THEREOF VINCERE BIOSCIENCES, INC. 2024-08-08 US disclosed
US-11845724-B2 USP30 inhibitors and uses thereof VINCERE BIOSCIENCES, INC. (US) 2023-12-19 US disclosed
WO-2023180189-A1 MPRO TARGETING ANTIVIRAL COMPOUNDS EXSCIENTIA AI LIMITED (GB) 2023-09-28 WO disclosed
US-20220315531-A1 USP30 INHIBITORS AND USES THEREOF VINCERE BIOSCIENCES, INC. 2022-10-06 US disclosed
EP-4028385-A1 USP30 INHIBITORS AND USES THEREOF Vincere Biosciences, Inc. (US) 2022-07-20 EP disclosed
US-20220196685-A1 PROBES FOR DETECTION OF COPPER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-06-23 US disclosed
US-4939131-A Certain cycloalkane-1,1-diphosphonic acids and derivatives thereof having the ability to treat diseases associated with abnormal calcium and phosphate metabolism THE PROCTER & GAMBLE COMPANY (US) 1990-07-03 US disclosed
US-4868164-A OSTEOPOROSIS, ARTHRITIS NORWICH EATON PHARMACEUTICALS, INC. (US) 1989-09-19 US disclosed
EP-0304962-A2 Novel diphosphonates and use thereof in pharmaceutical compositions THE PROCTER & GAMBLE COMPANY (US) 1989-03-01 EP disclosed
EP-0304961-A2 Novel diphosphonates and use thereof in pharmaceutical compositions THE PROCTER & GAMBLE COMPANY (US) 1989-03-01 EP disclosed
EP-0298553-A1 Methylene phosphonoalkylphosphinates, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism Norwich Eaton Pharmaceuticals, Inc. (US) 1989-01-11 EP disclosed
EP-0273514-A1 Novel bicyclic diphosphonate compounds and pharmaceutical compositions Norwich Eaton Pharmaceuticals, Inc. (US) 1988-07-06 EP disclosed
US-4687768-A OSTEOPOROSIS, ARTHRITIS THE PROCTER & GAMBLE COMPANY (US) 1987-08-18 US disclosed
EP-0189662-A1 Novel diphosphonates and use thereof in pharmaceutical compositions THE PROCTER & GAMBLE COMPANY (US) 1986-08-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12241902-B2 Probes for detection of copper SOD1, SOD3, CELF2 ALDH1A1 963/4885L3MBTL1 470/4885DPP4 4199/4885
US-11845724-B2 USP30 inhibitors and uses thereof USP30, USP28, USP1 ALDH1A1 2021/4885L3MBTL1 648/4885DPP4 1221/4885
US-20220315531-A1 USP30 INHIBITORS AND USES THEREOF USP30, USP28, USP1 ALDH1A1 2021/4885L3MBTL1 648/4885DPP4 1221/4885
US-20240262792-A1 USP30 INHIBITORS AND USES THEREOF USP30, USP28, USP1 ALDH1A1 2021/4885L3MBTL1 648/4885DPP4 1221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.