Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.64 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.64 |
| ▸ | ROS1 | P08922 | 1/20 | 0.64 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.64 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.62 |
| ▸ | FER | P16591 | 1/20 | 0.62 |
| ▸ | LTK | P29376 | 1/20 | 0.62 |
| ▸ | CDK8 | P49336 | 1/20 | 0.62 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.56 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.56 |
| ▸ | FLT3 | P36888 | 3/20 | 0.52 |
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17993494 | 0.90 | LRRK2 (0.54) | LRRK2ACVR1ROS1CDK5KMT2A | |
| SCHEMBL3409341 | 0.89 | LRRK2 (0.69) | LRRK2ACVR1ROS1CDK5PDGFRA | |
| SCHEMBL16712562 | 0.85 | ACVR1 (0.62) | LRRK2ACVR1ROS1CDK5PDGFRA | |
| SCHEMBL20442466 | 0.83 | CHEK1 (0.67) | LRRK2ACVR1ROS1CDK5PDGFRA | |
| SCHEMBL11890574 | 0.82 | FLT3 (0.54) | LRRK2ACVR1ROS1CDK5PDGFRA | |
| SCHEMBL11029136 | 0.82 | FLT3 (0.54) | LRRK2ACVR1ROS1CDK5PDGFRA | |
| 5-Fluoroisatin SCHEMBL7829877 | 0.82 | MAOB (0.69) | LRRK2KMT2AMEN1FLT3AGTR1 | |
| SCHEMBL11482314 | 0.82 | LRRK2 (0.48) | LRRK2ACVR1ROS1CDK5PDGFRA | |
| SCHEMBL9176425 | 0.79 | CYP1A2 (0.56) | LRRK2ACVR1ROS1CDK5FER | |
| SCHEMBL7496945 | 0.79 | CHEK1 (0.44) | LRRK2ACVR1ROS1CDK5PDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587029-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF INFLAMMATORY DISEASES | Invea Therapeutics, Inc. (US) | 2025-07-23 | — | — | EP | claimed |
| WO-2024059085-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF INFLAMMATORY DISEASES | INVEA THERAPEUTICS, INC. (US) | 2024-03-21 | — | — | WO | claimed |
| US-8202989-B2 | One step process for the preparation of substituted 5, 10-dihydrodibenzo [b,e][1, 4]diazepine-11-ones | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2012-06-19 | — | — | US | claimed |
| US-20100228023-A1 | ONE STEP PROCESS FOR THE PREPARATION OF SUBSTITUTED 5, 10-DIHYDRODIBENZO [b,e][1, 4]DIAZEPINE-11-ONES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2010-09-09 | — | — | US | claimed |
| US-20250206714-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF INFLAMMATORY DISEASES | INVEA THERAPEUTICS, INC. | 2025-06-26 | — | — | US | disclosed |
| US-8202989-B2 | One step process for the preparation of substituted 5, 10-dihydrodibenzo [b,e][1, 4]diazepine-11-ones | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2012-06-19 | — | — | US | disclosed |
| US-20100228023-A1 | ONE STEP PROCESS FOR THE PREPARATION OF SUBSTITUTED 5, 10-DIHYDRODIBENZO [b,e][1, 4]DIAZEPINE-11-ONES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2010-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100228023-A1 | ONE STEP PROCESS FOR THE PREPARATION OF SUBSTITUTED 5, 10-DIHYDRODIBENZO [b,e][1, 4]DIAZEPINE-11-ONES | BBOX1, CYP1B1, CYP4B1 | LRRK2 4616/4885ACVR1 949/4885ROS1 2526/4885 |
| US-20250206714-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF INFLAMMATORY DISEASES | PYCARD, NOD2, CASP1 | LRRK2 161/4885ACVR1 4434/4885ROS1 1556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.