Acrylic Acid

Acrylic Acid

SCHEMBL3625552

C=CC(=O)O.C=CC(=O)O.C=CC(=O)O.C=CC(=O)O.C=CC(=O)O.O

nearest known ligand 0.91

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.91
HSD17B10 Q99714 2/20 0.48
ALOX15 P16050 1/20 0.48
TSHR P16473 11/20 0.47
ALDH1A1 P00352 8/20 0.47
FGFR4 P22455 1/20 0.47
TP53 P04637 4/20 0.43
EGLN1 Q9GZT9 1/20 0.43
EGLN3 Q9H6Z9 1/20 0.43
AKT1 P31749 1/20 0.36
MAPK1 P28482 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
TGM2 P21980 1/20 0.32
HIF1A Q16665 2/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL9694843 1.00
Acrylic Acid SCHEMBL27997220 1.00 LMNA (0.91) LMNAHSD17B10ALOX15TSHRALDH1A1
Acrylic Acid SCHEMBL21612747 1.00 LMNA (0.91) LMNAHSD17B10ALOX15TSHRALDH1A1
Acrylic Acid SCHEMBL27528758 1.00 LMNA (0.91) LMNAHSD17B10ALOX15TSHRALDH1A1
Acrylic Acid SCHEMBL28796751 1.00 LMNA (0.91) LMNAHSD17B10ALOX15TSHRALDH1A1
Acrylic Acid SCHEMBL233722 1.00
Acrylic Acid SCHEMBL6048303 1.00
Acrylic Acid SCHEMBL7778846 0.96
Acrylic Acid SCHEMBL2373298 0.96 LMNA (0.83) LMNAHSD17B10ALOX15TSHRALDH1A1
Acrylic Acid SCHEMBL7778848 0.96

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1788009-B1 Process for the solid freeform fabrication of hearing aids using curable acrylate oligomers HENKEL CORP (US) 2010-03-24 EP claimed
EP-0711802-B1 Method of indicating a cure point for ultraviolet radiation curing compositions by color change DOW CORNING (US) 1999-10-06 EP claimed
CN-114497432-B Electrode, method of manufacturing the same, electrode element, and nonaqueous electrolyte storage element 株式会社理光 2024-07-09 CN disclosed
CN-111492508-B Electrode, method of manufacturing the same, electrode element, and nonaqueous electrolyte storage element 株式会社理光 2023-10-20 CN disclosed
US-6048667-A FREE RADICALS OR CATION POLYMERIZABLE OR PHOTOCROSSLINKABLE MONOMERS, SUBSTRATES AND PHOTOINITIATORS, BONDING WITH SUBSTRATES CIBA SPECIALTY CHEMICALS CORP. (US) 2000-04-11 US disclosed
US-5239029-A An adhesives comprising polyphosphazenes, unsaturated pentaerythritol acrylate, bis(4-acryloxydialkoxyphenyl)propane ; transparency, adhesion, waterproofing; protective coatings IDEMITSU PETROCHEMICAL COMPANY LIMITED (JP) 1993-08-24 US disclosed